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抗凝治疗下的牙科种植回顾性分析。

A retrospective analysis of dental implantation under anticoagulant treatment.

机构信息

Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.

Department of Oral and Maxillofacial Surgery, Sorasky Medical Center, Tel Aviv, Israel.

出版信息

Clin Oral Investig. 2021 Mar;25(3):1001-1009. doi: 10.1007/s00784-020-03389-z. Epub 2020 Jun 6.

DOI:10.1007/s00784-020-03389-z
PMID:32506326
Abstract

OBJECTIVES

To present our experience treating patients who have undergone dental implantation under no change in their constant anticoagulant treatment.

PATIENTS AND METHODS

A retrospective study on patients who have undergone dental implantation. The study group consisted of patients under oral anticoagulants for at least 6 months before dental implantation. The control group was consisted of healthy patients with no oral anticoagulant treatment. Bleeding events were recorded and treated during the first 2 weeks postoperatively.

RESULTS

A total of 193 patients were included in the study. Seventy-two of them who were under anticoagulants served as a study group and the rest (121 patients) served as a control group. Mean age: 65 years old in the study group and 59 years old in the control group. Gender: male to female ratio was higher in the study group and lower in the control group. Four patients in the study group and 7 patients in the control group presented postoperative bleeding and were treated successfully by additional local hemostasis methods.

CONCLUSION

With the limitation of this study, it can be concluded that patients under oral anticoagulant treatment can undergo dental implantation safely. Bleeding events are rare and can be controlled by local hemostasis.

CLINICAL RELEVANCE

Prior to dental implant insertion, patients under oral anticoagulants can continue their constant medical treatment. The procedure can be performed on outpatient basis under local hemostasis.

摘要

目的

介绍我们在患者持续使用抗凝药物治疗不变的情况下进行牙科种植的经验。

患者和方法

这是一项针对接受过牙科种植的患者的回顾性研究。研究组由至少在牙科种植前 6 个月开始接受口服抗凝治疗的患者组成。对照组由未接受口服抗凝治疗的健康患者组成。记录并在术后 2 周内治疗出血事件。

结果

共有 193 名患者入组。其中 72 名接受抗凝治疗的患者作为研究组,其余 121 名患者作为对照组。平均年龄:研究组为 65 岁,对照组为 59 岁。性别:研究组的男女比例较高,对照组较低。研究组中有 4 名患者和对照组中有 7 名患者出现术后出血,并通过额外的局部止血方法成功治疗。

结论

受本研究的限制,可以得出结论,接受口服抗凝治疗的患者可以安全地进行牙科种植。出血事件很少见,可以通过局部止血来控制。

临床相关性

在进行牙科种植之前,接受口服抗凝治疗的患者可以继续接受常规的药物治疗。该手术可以在门诊基础上进行,并采用局部止血。

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本文引用的文献

1
The role of direct oral anticoagulants in the management of venous thromboembolism.直接口服抗凝剂在静脉血栓栓塞症管理中的作用。
Am J Manag Care. 2017 Dec;23(20 Suppl):S383-S390.
2
Aspirin, Plavix, and Other Antiplatelet Medications: What the Oral and Maxillofacial Surgeon Needs to Know.
Oral Maxillofac Surg Clin North Am. 2016 Nov;28(4):497-506. doi: 10.1016/j.coms.2016.06.003. Epub 2016 Aug 29.
3
Antiplatelet therapy and exodontia.抗血小板治疗与拔牙术
J Am Dent Assoc. 2015 Nov;146(11):851-6. doi: 10.1016/j.adaj.2015.04.024.
接受牙科手术的患者的抗血栓治疗围手术期管理:文献系统评价和网络荟萃分析。
Int J Environ Res Public Health. 2023 Mar 28;20(7):5293. doi: 10.3390/ijerph20075293.
4
Management of an Active Oral Bleed Following Dental Implant Therapy Using Lidocaine and Epinephrine Injection in the Presence of an Oral Anticoagulant: A Clinical Report.在口服抗凝剂存在的情况下,使用利多卡因和肾上腺素注射治疗牙种植术后口腔活动性出血:一份临床报告。
Cureus. 2022 Sep 23;14(9):e29495. doi: 10.7759/cureus.29495. eCollection 2022 Sep.
5
Bleeding disorders in implant dentistry: a narrative review and a treatment guide.种植牙科中的出血性疾病:叙述性综述与治疗指南
Int J Implant Dent. 2022 Apr 16;8(1):20. doi: 10.1186/s40729-022-00418-2.
6
Dental implants and risk of bleeding in patients on oral anticoagulants: a systematic review and meta-analysis.牙种植体和口服抗凝剂患者出血风险:系统评价和荟萃分析。
Int J Implant Dent. 2021 Aug 25;7(1):82. doi: 10.1186/s40729-021-00364-5.
4
Dentists' approach to patients on anti-platelet agents and warfarin: a survey of practice.牙医对服用抗血小板药物和华法林患者的治疗方法:一项实践调查。
J Ir Dent Assoc. 2010 Feb-Mar;56(1):28-31.
5
The management of patients on chronic Coumadin therapy undergoing subsequent surgical procedures.接受慢性华法林治疗的患者在后续外科手术中的管理。
Am Surg. 1994 Jul;60(7):542-6; discussion 546-7.