Department of Pharmaceutical Sciences and Pharmaceutics, Faculty of Pharmacy, Applied Science Private University, Amman, Jordan.
Faculty of Medicine, University of JORDAN, Amman, Jordan.
J Viral Hepat. 2020 Nov;27(11):1108-1118. doi: 10.1111/jvh.13342. Epub 2020 Jul 2.
This observational study was designed to assess the prevalence, knowledge and attitude of pregnant females towards hepatitis B infection, in addition to their perspective of the healthcare practice about HBV in Jordan. A randomly selected group of pregnant females visiting public gynaecology clinics in Jordan were approached to participate in the study. Blood samples were collected from the participants, and HBV markers were detected in their serum using specialized ELISA Kits to assess for the prevalence of infection. Knowledge and attitude of participants was assessed via a developed and validated questionnaire. Statistical analysis was conducted using the Statistical Package for the Social Sciences (SPSS) version 24. Blood samples (n = 300) from 330 pregnant females were collected. The prevalence of hepatitis B surface antigen (HBsAg) among the pregnant females was found to be 5%. Anti-HBs and anti-HBc were found to be 33.3% and 7%, respectively. No significant correlation between age, socio-economic status and educational level was found with HBsAg positivity. Limited knowledge regarding HBV was revealed among the pregnant females (9.1%-41.3%, P < .05). The majority had a positive attitude regarding HBV vaccination and antiviral medications in case of infectivity. More than 90% agreed on the present lack of counselling and screening of HBV they obtained during their first perinatal visit to the gynaecology clinics. This study revealed a lack of knowledge on HBV, and low counselling and screening received were reported. Policymakers need to introduce new interventions to improve the current awareness of patients and gynaecologists regarding hepatitis B infection.
本观察性研究旨在评估约旦孕妇对乙型肝炎感染的流行情况、知识水平和态度,以及她们对乙型肝炎病毒(HBV)医疗保健实践的看法。研究人员随机选取了约旦公共妇科诊所的一组孕妇,邀请她们参与研究。从参与者中采集血样,使用专门的酶联免疫吸附试验(ELISA)试剂盒检测血清中的 HBV 标志物,以评估感染的流行情况。通过开发和验证的问卷评估参与者的知识和态度。使用社会科学统计软件包(SPSS)版本 24 进行统计分析。共采集了 330 名孕妇的 300 份血样。研究发现,孕妇中乙型肝炎表面抗原(HBsAg)的流行率为 5%。抗-HBs 和抗-HBc 的阳性率分别为 33.3%和 7%。年龄、社会经济地位和教育水平与 HBsAg 阳性率之间无显著相关性。研究结果表明,孕妇对 HBV 的认识有限(9.1%-41.3%,P<.05)。大多数孕妇对 HBV 疫苗接种和抗病毒药物持积极态度,如果感染了乙型肝炎病毒。超过 90%的孕妇同意目前在妇科诊所首次进行围产期就诊时缺乏乙型肝炎病毒的咨询和筛查。本研究表明,孕妇对 HBV 的认识不足,接受的咨询和筛查较少。政策制定者需要引入新的干预措施,以提高患者和妇科医生对乙型肝炎感染的认识。