Department of Infectious Diseases, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Front Public Health. 2022 Jun 14;10:873741. doi: 10.3389/fpubh.2022.873741. eCollection 2022.
The objective of this project was to explore the distribution and related factors of blood lead and the association between blood lead and hepatitis B core antibody (HBcAb). All the data were from the U.S. National Health and Nutrition Examination Survey (NHANES). In total, 15,097 (aged 20-80 years) participants were included. Participants without a history of blood transfusion were more likely to be exposed to lower levels of blood lead [-2.30 (-3.13, -1.47) for HBcAb (-) and -2.23 (-4.54, 0.08) for HBcAb (+)]. The odds ratio () of HBcAb (+) increased with blood lead and the result was 1.09 (1.06, 1.12). This study showed that older adults, men, people with a lower education level, a lower ratio of family income to poverty (PIR), a lower body mass index (BMI), or a history of blood transfusion, people who lived with a companion or with a total number of people in the family >3, people living in the United States for a longer time, U.S. citizens by birth or naturalization, and people not born in the United States were associated with higher blood lead exposure, and blood lead had a positive association with HBcAb (+).
本项目的目的是探讨血铅的分布及其相关因素，以及血铅与乙型肝炎核心抗体（HBcAb）之间的关系。所有数据均来自美国国家健康和营养检查调查（NHANES）。共纳入 15097 名（年龄 20-80 岁）参与者。无输血史的参与者更有可能接触到较低水平的血铅[-2.30（-3.13，-1.47）对 HBcAb（-）和-2.23（-4.54，0.08）对 HBcAb（+）]。HBcAb（+）的比值比（OR）随血铅水平升高而升高，结果为 1.09（1.06，1.12）。本研究表明，老年人、男性、受教育程度较低者、家庭收入与贫困率（PIR）比值较低者、体重指数（BMI）较低者或有输血史者、与同伴同住或家庭人口总数>3 者、在美国居住时间较长者、出生或入籍的美国公民以及非美国出生者与更高的血铅暴露相关，血铅与 HBcAb（+）呈正相关。
