Otsuki Mika
Graduate School of Health Sciences, Hokkaido University.
Brain Nerve. 2020 Jun;72(6):611-621. doi: 10.11477/mf.1416201571.
I have introduced primary progressive aphasia (PPA) with regard to frontotemporal lobar degeneration (FTLD) and evaluated the following elementary language symptoms for its diagnosis: agrammatism in speech production, apraxia of speech, phonemic paraphasia, naming impairment, impairment of single-word comprehension, and repetition. Furthermore, I have described the clinical symptoms, causative lesions, and pathological findings of three PPA variants -nonfluent/agrammatic, semantic, and logopenic PPA- according to the criteria proposed by Gorno-Tempni et al. (2011).
我已介绍了与额颞叶变性(FTLD)相关的原发性进行性失语(PPA),并评估了以下用于其诊断的基本语言症状:言语产生中的语法缺失、言语失用、音素性错语、命名障碍、单词理解障碍和复述。此外,我还根据戈尔诺 - 滕皮尼等人(2011年)提出的标准,描述了三种PPA变体——非流利/语法缺失型、语义型和音韵性失语型PPA的临床症状、致病病变和病理发现。