普遍艾滋病毒检测和治疗（UTT）与慢性病筛查和治疗相结合：SEARCH 研究。
Universal HIV Testing and Treatment (UTT) Integrated with Chronic Disease Screening and Treatment: the SEARCH study.
机构信息
Division of HIV, Infectious Diseases & Global Medicine, San Francisco General Hospital / University of California, San Francisco, UCSF Box 0874, San Francisco, CA, 94143-0874, USA.
Infectious Diseases Research Collaboration, Kampala, Uganda.
出版信息
Curr HIV/AIDS Rep. 2020 Aug;17(4):315-323. doi: 10.1007/s11904-020-00500-7.
PURPOSE OF REVIEW
The growing burden of untreated chronic disease among persons with HIV (PWH) threatens to reverse heath gains from ART expansion. Universal test and treat (UTT)'s population-based approach provides opportunity to jointly identify and treat HIV and other chronic diseases. This review's purpose is to describe SEARCH UTT study's integrated disease strategy and related approaches in Sub-Saharan Africa.
RECENT FINDINGS
In SEARCH, 97% of adults were HIV tested, 85% were screened for hypertension, and 79% for diabetes at health fairs after 2 years, for an additional $1.16/person. After 3 years, population-level hypertension control was 26% higher in intervention versus control communities. Other mobile/home-based multi-disease screening approaches have proven successful, but data on multi-disease care delivery are extremely limited and show little effect on clinical outcomes. Integration of chronic disease into HIV in the UTT era is feasible and can achieve population level effects; however, optimization and implementation remain a huge unmet need.
目的综述
未经治疗的慢性疾病在艾滋病毒感染者（PWH）中的负担日益加重，有可能逆转因抗逆转录病毒治疗（ART）扩展而取得的健康成果。普遍检测和治疗（UTT）的基于人群的方法为共同发现和治疗艾滋病毒和其他慢性疾病提供了机会。本综述的目的是描述在撒哈拉以南非洲进行的 SEARCH UTT 研究的综合疾病策略和相关方法。
最近的发现
在 SEARCH 中，97%的成年人在健康博览会上接受了艾滋病毒检测，85%接受了高血压筛查，79%接受了糖尿病筛查，每人额外花费 1.16 美元。2 年后，干预社区的人群高血压控制水平比对照社区高 26%。其他移动/家庭为基础的多种疾病筛查方法已被证明是成功的，但关于多种疾病护理提供的数据极其有限，对临床结果几乎没有影响。在 UTT 时代将慢性疾病纳入艾滋病毒治疗是可行的，并且可以实现人群水平的效果；然而，优化和实施仍然是一个巨大的未满足的需求。
Zotero 插件