Liu Q H
Cancer Institute, China University of Medical Sciences, Shenyang.
Zhonghua Zhong Liu Za Zhi. 1988 Nov;10(6):430-3.
Of 100 cases of gastric cancer, free cancer cells in the abdominal cavity were detected in 32 (32%). In serosal typing, the free cancer cells were often found in the tendonoid (62.2%) and diffused colour types (60.0%). When the area of serosa invasion was over 20 cm2, the positive rate was 56.6% and only 2.5% if below 20 cm2. Incidence of free cancer cells was related to the depth of cancer infiltration, being often found in S2 and S3. It was also related to the pathologic characteristics of gastric cancer. Free cancer cells were often seen in infiltrating type (Borrmann 3,4); histologically differentiated or undifferentiated adenocarcinomas; nest or diffuse growing types. In patients without metastasis in the peritoneum (P0), the positive rate was 26.1%. This study proved that Chen's serosal classification is correct and useful in assessing whether the cancer cells have penetrated through the serosa during operation. Different treatment should be used in cases with different serosal types. In addition to rational surgical operation, killing of the free cancer cells should be considered in tendonoid and diffused colour serosal types so as to prevent peritoneal metastasis.
在100例胃癌患者中，32例（32%）检测到腹腔游离癌细胞。在浆膜分型中，游离癌细胞常见于腱样型（62.2%）和弥漫着色型（60.0%）。当浆膜侵犯面积超过20 cm²时，阳性率为56.6%，而低于20 cm²时仅为2.5%。游离癌细胞的发生率与癌浸润深度有关，常见于S2和S3期。它还与胃癌的病理特征有关。游离癌细胞常见于浸润型（Borrmann 3、4型）；组织学上为分化或未分化腺癌；巢状或弥漫生长型。在无腹膜转移（P0）的患者中，阳性率为26.1%。本研究证明陈氏浆膜分类在评估手术中癌细胞是否穿透浆膜方面是正确且有用的。不同浆膜类型的病例应采用不同的治疗方法。除合理的手术操作外，对于腱样型和弥漫着色型浆膜类型，应考虑杀灭游离癌细胞以预防腹膜转移。
