Quilla Maria Henrietta D P, Paller Vachel Gay V
Parasitology Research Laboratory, Animal Biology Division, Institute of Biological Sciences, College of Arts and Sciences, University of the Philippines Los Baños, Los Baños, Laguna Philippines.
J Parasit Dis. 2020 Jun;44(2):338-348. doi: 10.1007/s12639-019-01189-1. Epub 2020 Jan 2.
Rats are recognized as reservoir hosts of several pathogens that pose a threat to human health. Although rats are reported to be hosts of a large number of pathogens, a survey of carried by rats in various settings such as residential, agroforestry, and agricultural areas in the Philippines has not been conducted. A total of 90 rats composed of , , and were collected through trapping in selected residential, agroforestry, and agricultural areas in Los Baños Laguna, Philippines. The overall prevalence of among rats was 21.11%. Among the rat species collected, showed the highest prevalence (55.56%), followed by (14.29%), then (5.36%) (differences significant at < 0.05). Moreover, residential areas had the highest prevalence of infection (50%), followed by agroforestry and agricultural areas at 6.7% each (significant at < 0.05). However, the difference in infection between male (11.43%; 4/35) and female (27.27%; 15/55) rats was not significant ( > 0.05). Most of the infected rats were moderately infected (68.42%), while few were lightly and severely infected (15.78% each). Lastly, the presence of in liver is suggestive of presence of lymphocytes, amyloid, granuloma, and the occurrence of necrosis, hypertrophy, fibrosis, and cholestasis in the liver of the host. Capillariasis could be occurring in Philippine human populations, hence there is need for screening the population with appropriate means and to create awareness of this emerging disease.
大鼠被认为是几种对人类健康构成威胁的病原体的储存宿主。尽管据报道大鼠是大量病原体的宿主，但尚未在菲律宾的住宅、农林和农业等不同环境中对大鼠携带的病原体进行调查。通过在菲律宾拉古纳洛斯巴尼奥斯的选定住宅、农林和农业地区设陷阱捕获，共收集了90只大鼠，包括[具体鼠种1]、[具体鼠种2]和[具体鼠种3]。大鼠中[病原体名称]的总体感染率为21.11%。在所收集的鼠种中，[具体鼠种1]的感染率最高（55.56%），其次是[具体鼠种2]（14.29%），然后是[具体鼠种3]（5.36%）（差异在P < 0.05时显著）。此外，住宅区的[病原体名称]感染率最高（50%），其次是农林区和农业区，各为6.7%（在P < 0.05时显著）。然而，雄性大鼠（11.43%；4/35）和雌性大鼠（27.27%；15/55）之间的[病原体名称]感染差异不显著（P > 0.05）。大多数感染大鼠为中度感染（68.42%），而轻度和重度感染的较少（各为15.78%）。最后，肝脏中[病原体名称]的存在提示宿主肝脏中存在淋巴细胞、淀粉样蛋白、肉芽肿，以及坏死、肥大、纤维化和胆汁淤积的发生。菲律宾人群中可能正在发生毛细线虫病，因此需要采用适当方法对人群进行筛查，并提高对这种新出现疾病的认识。
