Department of Orthopedics, First Affiliated Hospital of Soochow University, Soochow 215006, Jiangsu Province, China.
World J Gastroenterol. 2010 Feb 14;16(6):698-702. doi: 10.3748/wjg.v16.i6.698.
Capillaria hepatica (C. hepatica) is a parasitic nematode causing hepatic capillariasis in numerous mammals. Ecologic studies showed that the first hosts of C. hepatica were rodents, among which rats had relatively high infection rates, which explains why C. hepatica spreads globally. Anatomical studies showed that the liver was the principal site of colonization by these parasites and physical damage tended to occur. Although C. hepatica might lead to serious liver disorders, relevant clinical reports were rare, because of the non-specific nature of clinical symptoms, leading to misdiagnosis. This review mainly focuses on the biological characteristics and epidemiology of C. hepatica in China and histopathologic changes in the liver, with expectation of gaining a better understanding of the disease and seeking more effective treatment.
肝毛细线虫（C. hepatica）是一种寄生性线虫，可引起许多哺乳动物的肝毛细线虫病。生态研究表明，肝毛细线虫的第一宿主是啮齿动物，其中大鼠的感染率相对较高，这解释了为什么肝毛细线虫会在全球范围内传播。解剖学研究表明，肝脏是这些寄生虫定植的主要部位，并且容易发生物理损伤。尽管肝毛细线虫可能导致严重的肝脏疾病，但由于临床症状的非特异性，相关的临床报告很少，导致误诊。本综述主要关注中国肝毛细线虫的生物学特性和流行病学以及肝脏的组织病理学变化，以期更好地了解该疾病并寻求更有效的治疗方法。
