孟加拉国贾索尔的急性中毒情况。

The Scenario of Acute Poisoning in Jashore, Bangladesh.

作者信息

Acherjya G K, Ali M, Alam A B M S, Rahman M M, Mowla S G M

机构信息

Jashore Medical College and Hospital, Jashore, Bangladesh.

National Institute of Cancer Research and Hospital, Mohakhali, Dhaka, Bangladesh.

出版信息

J Toxicol. 2020 May 19;2020:2109673. doi: 10.1155/2020/2109673. eCollection 2020.

DOI:10.1155/2020/2109673

PMID:32508916

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7254068/

Abstract

BACKGROUND

Acute poisoning is a common scenario in the emergency department of any general hospital globally, but its pattern may vary in different parts of the world and even may be a different regional variation in the same country.

OBJECTIVE

Our recent study aims to assess the demographic characteristics, psychological aspect, pattern, and treatment outcome in different acute poisoning.

METHOD

The present cross-sectional study was conducted in the medicine department of Jashore Medical College and Hospital from 1 January to 30 June 2018, which recruited 487 eligible cases of admitted acute poisoning patients.

RESULTS

The study reveals that the total incidence of acute poisoning in Jashore, Bangladesh, is 17.1 per 100,000 populations over a 6-month period. The mean age of our study population was 27 ± 11 (SD) years with having significant female preponderance in acute poisoning (female: 253/52% and male: 234/48%; = 0.002). Female subjects were significantly younger than male ( <0.001). Moreover, the total suicidal intension of acute poisoning in our study was 97.3%, whereas the female subjects were more committed to suicidal attempts ( = 0.027). Organophosphorus compounds (OPCs) were the significant leading agents (66.1%, = 0.029) of acute poisoning, and even, it had been significantly used as suicidal intention of poisoning substance (65.1%, <0.001) in our observation. Muslim (97.5%, = 0.005), 10-29 year age group (68.0%, = 0.002), rural (99.2%), unmarried (51.3%), middle class (50.1%), students (48.9%), and secondary educational background population (76.4%) were more victimized of acute poisoning. Among different factors, familial disharmony constituted of 56.1% cases of suicidal attempt in acute poisoning. Finally, we had observed that the death incidence by acute poisoning in Jashore, Bangladesh, was 1.9 per 100,000 population over a 6-month period.

CONCLUSION

The recent study reveals that there is high incidence of acute poisoning in Jashore, Bangladesh, with a significant amount of death toll. Organophosphorus compound is the most common agent of deliberating self-poisoning in our study due to its easy availability in our agriculture-based community.

摘要

背景

急性中毒是全球任何一家综合医院急诊科的常见情况，但其模式在世界不同地区可能有所不同，甚至在同一个国家的不同地区也可能存在差异。

目的

我们最近的研究旨在评估不同急性中毒的人口统计学特征、心理方面、模式和治疗结果。

方法

本横断面研究于2018年1月1日至6月30日在贾索尔医学院和医院内科进行，招募了487例符合条件的急性中毒住院患者。

结果

研究表明，在6个月的时间里，孟加拉国贾索尔急性中毒的总发病率为每10万人中有17.1例。我们研究人群的平均年龄为27±11（标准差）岁，急性中毒中女性占显著优势（女性：253/52%，男性：234/48%；P = 0.002）。女性受试者明显比男性年轻（P<0.001）。此外，我们研究中急性中毒的自杀意图总比例为97.3%，而女性受试者更倾向于自杀未遂（P = 0.027）。有机磷化合物（OPC）是急性中毒的主要显著因素（66.1%，P = 0.029），甚至在我们的观察中，它作为中毒物质的自杀意图也显著（65.1%，P<0.001）。穆斯林（97.5%，P = 0.005）、10 - 29岁年龄组（68.0%，P = 0.002）、农村地区（99.2%）、未婚（51.3%）、中产阶级（50.1%）、学生（48.9%）以及具有中等教育背景的人群（76.4%）更容易遭受急性中毒。在不同因素中，家庭不和在急性中毒自杀未遂病例中占56.1%。最后，我们观察到，在6个月的时间里，孟加拉国贾索尔急性中毒的死亡率为每10万人中有1.9例。