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激光治疗口腔黏膜下纤维化的治疗效果——一项系统综述

Treatment outcomes of laser therapy in oral submucous fibrosis-a systematic review.

作者信息

Gondivkar Dr Shailesh M, Gadbail Dr Amol R, Sarode Dr Sachin C, Gondivkar Dr Rima S, Patil Shankargouda, Gaikwad Dr Rahul N, Yuwanati Dr Monal

机构信息

Department of Oral Medicine & Radiology, Government Dental College & Hospital, Nagpur, Maharashtra State, India.

Department of Dentistry, Indira Gandhi Government Medical College & Hospital, Nagpur, Maharashtra State, India.

出版信息

J Oral Biol Craniofac Res. 2020 Jul-Sep;10(3):253-258. doi: 10.1016/j.jobcr.2020.05.004. Epub 2020 May 18.

DOI:10.1016/j.jobcr.2020.05.004
PMID:32509514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7264056/
Abstract

BACKGROUND

The mainstay of oral submucous fibrosis (OSF) management is to increase the mouth opening; thereby improving oral functionalities. In modernized dentistry, laser therapy (LT) could play a major role for trismus relief in OSF patients. The present review was performed to systematically analyze the published literature on LT for OSF management.

METHODS

PubMed, Scopus, Web of Science and CINAHL databases were searched until June 2019 using suitable key words and the information was extracted according to the PRISMA guidelines. All full text papers that assessed efficacy of LT for OSF management without limitations on age, gender, ethnicity, or socioeconomic status of the participants were considered eligible. Participants were allocated to the LT alone or in adjunct to oral physiotherapy and medicinal treatment. Outcome parameters included the reduction in trismus. Review articles, case reports, editorial, conference abstracts and in vitro studies were excluded. No restriction was applied on date and language of the publications.

RESULTS

Out of 97 published papers, 7 studies met the inclusion criteria and were included for the analysis. All the studies were clinical and mainly included stage II and III OSF patients. Although different laser types and other parameters were used, all the studies reported improvement in mouth opening in the range of 6.84 mm and 23.7 mm. Additionally, two studies noticed reduced burning sensation and increased tongue protrusion and cheek flexibility. : The LT can provide a promising and better means for relieving trismus and probably OSF-related other symptoms in moderate stages of the disease.

摘要

背景

口腔黏膜下纤维化(OSF)治疗的主要目的是增加开口度,从而改善口腔功能。在现代牙科中,激光治疗(LT)可能在缓解OSF患者的牙关紧闭方面发挥重要作用。本综述旨在系统分析已发表的关于LT治疗OSF的文献。

方法

使用合适的关键词检索截至2019年6月的PubMed、Scopus、Web of Science和CINAHL数据库,并根据PRISMA指南提取信息。所有评估LT治疗OSF疗效且对参与者的年龄、性别、种族或社会经济地位无限制的全文论文均被视为合格。参与者被分配接受单独的LT治疗或联合口腔物理治疗和药物治疗。观察指标包括牙关紧闭程度的降低。排除综述文章、病例报告、社论、会议摘要和体外研究。对出版物的日期和语言没有限制。

结果

在97篇已发表的论文中,7项研究符合纳入标准并被纳入分析。所有研究均为临床研究,主要纳入II期和III期OSF患者。尽管使用了不同类型的激光和其他参数,但所有研究均报告开口度改善范围在6.84毫米至23.7毫米之间。此外,两项研究注意到烧灼感减轻,舌突出度和颊部柔韧性增加。LT可为缓解中度OSF患者的牙关紧闭以及可能的其他OSF相关症状提供一种有前景且更好的方法。

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Lasers Med Sci. 2018 Nov;33(8):1739-1745. doi: 10.1007/s10103-018-2531-8. Epub 2018 Jun 8.
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Impact of oral submucous fibrosis on oral health-related quality of life: A condition-specific OHRQoL-OSF instrument analysis.口腔黏膜下纤维性变对口腔健康相关生活质量的影响:一种特定于疾病的 OHROoL-OSF 工具分析。
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Quality of Life-related "Patient-reported Outcome Measures" in Oral Submucous Fibrosis Patients.口腔黏膜下纤维化患者中与生活质量相关的“患者报告结局指标”
J Contemp Dent Pract. 2018 Mar 1;19(3):331-338.
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