Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Middle Renmin Road 139, Changsha 410000, China.
Department of Cardiovascular Surgery, The People's Hospital of Hunan Province, West Jiefang Road 61, Changsha 410000, China.
Biomed Res Int. 2020 May 14;2020:3805385. doi: 10.1155/2020/3805385. eCollection 2020.
To evaluate the early and midterm results of a modified sliding anastomosis technique in patients with aortic coarctation.
In this study, we reported a new repair method and compared the early and midterm outcome(s) with a conventional surgical approach for the management of patients with aortic coarctation. Forty-eight aortic coarctation patients with a narrowed segment length longer than 2 cm were operated at our department's pediatric surgical division. Excision of the coarctation and end-to-end anastomosis was carried out in twenty-five patients (control group). In contrast, a modified sliding technique was used for twenty-three cases in the observation group. Other accompanying cardiac anomalies simultaneously repaired included ventricular septal defect and patent ductus arteriosus. All patients received 1.5-10 years of postoperative echocardiographic follow-up.
This is a retrospective study carried out between January 2005 and June 2018. The study population consisted of forty-eight patients, which included twenty-six male and twenty-two female patients, with an average age of 5.2 ± 1.9 months (range, 28 days to 1 year). There was no mortality. The operative time, the number of intercostal artery disconnection, the drainage volume, and arm-leg systolic pressure gradient postoperation were less in the observation group as compared to the control group ( < 0.05). Also, cases with an anastomotic pressure gradient exceeding 10 mmHg during follow-up were less in the observation group as compared to the control group ( < 0.05). The postoperative complications encountered were chylothorax (control group 2 cases vs. observation group 0) and pulmonary atelectasis (control group 4 cases vs. observation group 1). They all, however, recovered after conservative treatment. Three patients in the control group underwent balloon angioplasty (reintervention) postoperative 2-4 years due to an increase in the anastomotic pressure gradient (>20 mmHg). After reintervention, the anastomotic pressure gradient reduced to 14 mmHg, 15 mmHg, and 17 mmHg, respectively.
For long segment aortic coarctation patients (longer than 2 cm), the use of the modified sliding anastomotic technique effectively helps to retain more autologous tissues, enlarge the diameter of the anastomosis, and decrease anastomotic tension and vascular injury. Therefore, this technique provides a new idea for the surgical treatment of aortic coarctations.
评估改良滑动吻合技术在主动脉缩窄患者中的早期和中期结果。
本研究报道了一种新的修复方法,并将其与传统手术方法治疗主动脉缩窄患者的早期和中期结果进行了比较。我们部门的小儿外科部门对 48 例主动脉缩窄患者进行了手术治疗,这些患者的缩窄段长度均大于 2cm。25 例患者(对照组)行缩窄段切除端端吻合术,23 例患者(观察组)行改良滑动吻合术。同期治疗的其他伴随的心脏畸形包括室间隔缺损和动脉导管未闭。所有患者术后接受 1.5-10 年的超声心动图随访。
这是一项 2005 年 1 月至 2018 年 6 月期间进行的回顾性研究。研究人群包括 48 例患者,其中男 26 例,女 22 例,平均年龄 5.2±1.9 个月(28 天至 1 岁)。无死亡病例。观察组的手术时间、切断的肋间动脉数量、术后引流量和臂-腿收缩压梯度均低于对照组(<0.05)。此外,观察组在随访中吻合口压力梯度超过 10mmHg 的病例数也少于对照组(<0.05)。观察组术后并发症为乳糜胸(对照组 2 例,观察组 0 例)和肺不张(对照组 4 例,观察组 1 例),均经保守治疗后痊愈。对照组有 3 例患者因吻合口压力梯度增加(>20mmHg)于术后 2-4 年行经皮球囊血管成形术(再介入)。再介入后,吻合口压力梯度分别降至 14mmHg、15mmHg 和 17mmHg。
对于长段主动脉缩窄患者(大于 2cm),改良滑动吻合技术可有效保留更多自体组织,扩大吻合口直径,降低吻合口张力和血管损伤,为主动脉缩窄的手术治疗提供了新的思路。