Li Shao-Jun, Feng Dan
Department of Pain Management, Wuhan First Hospital, Wuhan, Hubei Province, China.
J Int Med Res. 2025 Feb;53(2):300060518786903. doi: 10.1177/0300060518786903. Epub 2020 Jun 9.
Diabetic neuropathy (DN), one of the most common late complications of diabetes mellitus, significantly affects distinct regions of the nervous system. Pain management is challenging in DN as no effective therapies exist that reverse the pathological course of DN. Several drugs are recommended as the first-line treatment for painful DN, but these are associated with various side-effects in the long term. This report presents two cases with painful DN who underwent lumbar sympathetic pulsed radiofrequency combined with continuous epidural infusion. The two cases were followed for 30 days. Lumbar sympathetic pulsed radiofrequency combined with continuous epidural infusion offered effective pain relief and improved the health-related quality of life in two patients with DN over this time period.
糖尿病性神经病变（DN）是糖尿病最常见的晚期并发症之一，会显著影响神经系统的不同区域。由于目前尚无有效的疗法能逆转DN的病理进程，因此疼痛管理颇具挑战性。几种药物被推荐作为疼痛性DN的一线治疗药物，但长期使用这些药物会产生各种副作用。本报告介绍了两例疼痛性DN患者，他们接受了腰交感神经脉冲射频联合持续硬膜外输注治疗。对这两例患者进行了30天的随访。在此期间，腰交感神经脉冲射频联合持续硬膜外输注为两名DN患者提供了有效的疼痛缓解，并改善了与健康相关的生活质量。
