Pain Management Center, Centro Medico Zambrano Hellion, San Pedro Garza García, Nuevo Leon, Mexico.
Pain Research, The Pain Center at Grace Clinic, Texas Tech University HSC, Lubbock, Texas, U.S.A.
Pain Pract. 2021 Mar;21(3):343-347. doi: 10.1111/papr.12944. Epub 2020 Sep 24.
Trigeminal neuralgia (TN) is the most common cause of facial pain, leading to significant disability and impacting a patient's quality of life. Percutaneous procedures like continuous radiofrequency, pulsed radiofrequency (PRF), and combined continuous and pulsed radiofrequency have been studied in past years comparing different voltages in order to find more effective therapies with fewer complications (eg, numbness and masseter muscle weakness). With regard to young patients, there is still insufficient evidence on the most appropriate procedure in this patient population. PRF does not cause thermal damage. The mechanism of action involves delivering an electrical field to targeted nerves or tissues, modulating pain. We propose that bipolar pulsed radiofrequency (2 parallel cannulas) in the trigeminal ganglion produce a denser and larger field resulting in more effective controlled pain.
We present 2 cases of 40- and 48-year-old men with severe V2 to V3 TN who underwent bipolar PRF. We performed bipolar PRF on the trigeminal ganglion through the foramen ovale using two 22-gauge 100-mm cannulas with 10-mm active tips. Parameters used were voltage of 85 V, pulse width of 20 milliseconds, and total duration time of 6 minutes. Both patients reported complete relief of pain after the procedure, and at 2-year follow-up they were pain free and experienced a better quality of life. No complications were reported.
Bipolar PRF could be a non-neurodestructive option for young people with TN and deserves further investigation as a treatment option.
三叉神经痛(TN)是面部疼痛最常见的原因,导致显著的残疾,并影响患者的生活质量。近年来,人们研究了经皮程序,如连续射频、脉冲射频(PRF)和连续与脉冲射频的联合应用,以比较不同电压,从而找到更有效且并发症更少的治疗方法(例如麻木和咬肌无力)。对于年轻患者,针对这一患者群体,仍然缺乏最合适的程序的充分证据。PRF 不会造成热损伤。其作用机制涉及向目标神经或组织传递电场,从而调节疼痛。我们提出,在三叉神经节中应用双极脉冲射频(2 个平行套管)会产生更密集和更大的电场,从而更有效地控制疼痛。
我们介绍了 2 例 40 岁和 48 岁的 V2 至 V3 型 TN 严重患者,他们接受了双极 PRF 治疗。我们通过卵圆孔使用两根 22 号 100mm、带有 10mm 活性尖端的套管进行双极 PRF 治疗。使用的参数为 85V 电压、20 毫秒脉冲宽度和 6 分钟总持续时间。两位患者在手术后均报告疼痛完全缓解,2 年随访时无疼痛且生活质量得到改善。未报告任何并发症。
双极 PRF 可能是年轻 TN 患者的一种非神经破坏性选择,值得进一步研究作为一种治疗选择。