Candelori F, Minni A, Greco A, Scarpa A, Cassandro C, Cavaliere M, Bisognox M, Cassandro E, de Vincentiis M, Ralli M
Department of Sense Organs, University Sapienza of Rome, Italy.
Department of Medicine and Surgery, University of Salerno, Salerno, Italy.
Transl Med UniSa. 2020 May 31;22:15-18. eCollection 2020 May.
Pleomorphic adenomas are benign tumors of the salivary glands that mainly affect the lower pole of the superficial lobe of the parotid gland. The term "pleomorphic" refers to the epithelial and connective origin of the mass. The clinical presentation is typically that of asymptomatic swelling which increases in volume. Therapy consists in surgical removal of the tumor mass by parotidectomy with nerve preservation.
This clinical case describes an interesting case of pleomorphic adenoma of the parotid gland in a 62-year-old patient. The patient presented with a long history of an asymptomatic mildly worsening swelling of the left parotid region. The peculiarity of the clinical case is the dimension of the adenoma (9x5x9 cm) and the presence of a thyroid incidentaloma (TI), consisting of a thyroid multinodular goiter composed of nodules, the largest of which measured 8 cm in diameter. This mass dislocated the laryngotracheal axis, compressed the larynx and caused the reduction of the respiratory space, making orotracheal intubation difficult and determining the need to perform a tracheotomy.
Benign pleomorphic adenomas can potentially reach large sizes if untreated. Socio-economic problems may be the reason for late diagnosis.
多形性腺瘤是涎腺的良性肿瘤，主要累及腮腺浅叶下极。“多形性”一词指该肿物起源于上皮和结缔组织。临床表现通常为无症状性肿胀，且体积会增大。治疗方法是通过保留神经的腮腺切除术切除肿瘤肿物。
本临床病例描述了一名62岁患者的腮腺多形性腺瘤的有趣病例。患者有长期的左侧腮腺区无症状性轻度肿胀且逐渐加重的病史。该临床病例的特殊之处在于腺瘤的大小（9×5×9厘米）以及存在甲状腺偶发瘤（TI），其为一个由结节组成的甲状腺多结节性甲状腺肿，其中最大的结节直径达8厘米。该肿物使喉气管轴移位，压迫喉部并导致呼吸空间减小，使得经口气管插管困难，并决定需要进行气管切开术。
如果不进行治疗，良性多形性腺瘤可能会长得很大。社会经济问题可能是诊断延迟的原因。
