Nielsen Suzanne, Sanfilippo Paul, Picco Louisa, Bruno Raimondo, Kowalski Michala, Wood Pene, Larney Sarah
Monash Addiction Research Centre, Eastern Health Clinical School, Monash University, Melbourne, Australia.
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Int J Clin Pharm. 2021 Apr;43(2):420-429. doi: 10.1007/s11096-020-01074-5. Epub 2020 Jun 12.
Background Pharmacists have a key role to play in identifying and responding to emerging clinical problems with prescribed opioids. A pilot study in Australia examined the implementation of screening and brief intervention (Routine Opioid Outcome Monitoring [ROOM]) to identify and respond to opioid-related problems in community pharmacies. In this implementation study, the rate of screening varied considerably between pharmacies. Objective The aim of this study was to examine pharmacist characteristics associated with implementation of ROOM. Setting Community pharmacies in Victoria and New South Wales, Australia. Methods We implemented a validated computer-facilitated screening (ROOM), combined with brief intervention for opioid-related problems based on a widely accepted framework for monitoring outcomes. In this analysis, we examined the correlates of ROOM completion for individual pharmacists. Negative binomial regression was used to identify baseline predictors of greater screening, with the number of ROOM screens as the dependent (outcome) variable and pharmacist demographics, knowledge, confidence and comfort responding to prescription opioids problems, and attitudes towards evidence based practice examined as independent (predictor) variables. Main outcome measure Number of screens completed by an individual pharmacist as reported in follow-up surveys by pharmacist. Results Fewer years of practice was associated with a greater number of screenings conducted. On average, each additional decade of practice was associated with a 31% (95% CI 0%, 53%) reduction in the number of screenings undertaken by pharmacists. A multivariable analysis revealed that each additional decade practicing, lower knowledge of naloxone and lower confidence in identifying unmanaged pain were all independently associated with reduced engagement in screening after controlling for other variables. Conclusion Findings from this pilot study identified potential barriers to implementing opioid outcome monitoring. Further studies could test different groups of community pharmacists' experience of different barriers when implementing monitoring outcomes with prescribed opioids, to inform future implementation and clinical practice.
背景 药剂师在识别和应对处方阿片类药物新出现的临床问题方面发挥着关键作用。澳大利亚的一项试点研究考察了筛查与简短干预措施(常规阿片类药物结果监测[ROOM])的实施情况,以识别和应对社区药房中与阿片类药物相关的问题。在这项实施研究中,各药房之间的筛查率差异很大。目的 本研究旨在考察与ROOM实施相关的药剂师特征。地点 澳大利亚维多利亚州和新南威尔士州的社区药房。方法 我们实施了一项经过验证的计算机辅助筛查(ROOM),并结合基于广泛接受的结果监测框架对阿片类药物相关问题进行简短干预。在本分析中,我们考察了个体药剂师完成ROOM的相关因素。采用负二项回归来确定更多筛查的基线预测因素,以ROOM筛查次数作为因(结果)变量,药剂师的人口统计学特征、知识、对处方阿片类药物问题做出反应的信心和舒适度,以及对循证实践的态度作为自变量(预测因素)进行考察。主要结局指标 药剂师在后续调查中报告的个体药剂师完成的筛查次数。结果 执业年限较少与进行的筛查次数较多相关。平均而言,每增加一个十年的执业时间,药剂师进行的筛查次数就会减少31%(95%CI 0%,53%)。多变量分析显示,在控制其他变量后,每增加一个十年的执业时间、对纳洛酮的了解较少以及识别未得到处理的疼痛的信心较低,均与筛查参与度降低独立相关。结论 这项试点研究的结果确定了实施阿片类药物结果监测的潜在障碍。进一步的研究可以测试不同组别的社区药剂师在对处方阿片类药物实施结果监测时遇到不同障碍的经历,以为未来的实施和临床实践提供参考。