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“它能救你的命,我就知道这么多。”澳大利亚地区接受阿片类药物替代治疗的人群使用纳洛酮带回家的参与障碍与促进因素:一项探索性研究。

"It can save your life, that's all I know," barriers and facilitators for engagement in take-home naloxone for people receiving opioid substitution treatment in regional Australia: An explorative study.

作者信息

Natale Isabella, Harvey Craig, Wood Pene, Anderson Karen

机构信息

Drugs and Alcohol Services, Barwon Health, Geelong.

La Trobe University, Bendigo, Australia.

出版信息

Qual Res Med Healthc. 2023 Jul 19;7(2):10868. doi: 10.4081/qrmh.2023.10868.

DOI:10.4081/qrmh.2023.10868
PMID:37692452
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10483482/
Abstract

Engagement in take-home naloxone (THN) programs by people receiving opioid substitution treatment (OST) in Australia is low despite methadone being a significant contributor to opioid overdose deaths. Our aim was to explore barriers and facilitators for OST patients to engage in THN. We used a descriptive qualitative design with thematic analysis to gain insight into naloxone uptake by people engaged in an OST program in regional Australia. Eleven participants were interviewed; eight had previously engaged with THN. Barriers to THN included limited knowledge and understanding, lack of information, and not personally experiencing an overdose. Facilitators included having a traumatic experience of overdose, knowledge and understanding of THN and overdose, empowerment in carrying naloxone, and expanding THN programs. Support for the expansion of THN programs is desired among participants, and widespread peer distribution is understood to be the key to success. This study found that prior traumatic experience of overdose facilitates acceptance of THN, and being offered THN was the most important factor in engagement. Less clear is how to engage people who lack a traumatic overdose experience.

摘要

尽管美沙酮是阿片类药物过量死亡的一个重要因素,但在澳大利亚接受阿片类药物替代治疗(OST)的人群参与带回家纳洛酮(THN)项目的比例较低。我们的目的是探讨OST患者参与THN的障碍和促进因素。我们采用描述性定性设计和主题分析,以深入了解澳大利亚地区参与OST项目的人群对纳洛酮的接受情况。采访了11名参与者;其中8人之前参与过THN。THN的障碍包括知识和理解有限、信息缺乏以及没有亲身经历过过量用药。促进因素包括有过量用药的创伤经历、对THN和过量用药的知识和理解、携带纳洛酮的自主权以及扩大THN项目。参与者希望扩大THN项目,并且广泛的同伴分发被认为是成功的关键。这项研究发现,之前过量用药的创伤经历有助于接受THN,而提供THN是参与的最重要因素。对于如何让那些没有过量用药创伤经历的人参与进来,还不太清楚。

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本文引用的文献

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What predicts pharmacists' engagement with opioid-outcome screening? Secondary analysis from an implementation study in community pharmacy.哪些因素可预测药剂师参与阿片类药物结果筛查?一项社区药房实施研究的二次分析。
Int J Clin Pharm. 2021 Apr;43(2):420-429. doi: 10.1007/s11096-020-01074-5. Epub 2020 Jun 12.
2
Addiction stigma and the production of impediments to take-home naloxone uptake.成瘾污名化以及阻碍携带式纳洛酮获取的因素的产生。
Health (London). 2022 Mar;26(2):139-161. doi: 10.1177/1363459320925863. Epub 2020 Jun 12.
3
Designing, implementing and evaluating the overdose response with take-home naloxone model of care: An evaluation of client outcomes and perspectives.设计、实施和评估带纳洛酮回家护理模式的过量反应:对客户结果和观点的评估。
Drug Alcohol Rev. 2020 Jan;39(1):55-65. doi: 10.1111/dar.13015. Epub 2019 Nov 27.
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The uptake of the pharmacy-dispensed naloxone kit program in Ontario: A population-based study.安大略省药房配发纳洛酮试剂盒计划的采用:一项基于人群的研究。
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