Omiadze S, Nikolaishvili M, Shishniashvili T
1Salome Omiadze's Dental Clinic, Georgia.
2Beritashvili Center of Experimental Biomedicine, Georgia.
Georgian Med News. 2020 Apr(301):82-86.
The study of clinical and biochemical processes in the oral cavity determined changes in the entire biochemical spectrum of the oral cavity in 132 patients aged 20-40 years with various forms of periodontitis. Similar follow-ups were divided into three groups in the main group with mild to moderate severity of periodontitis with a 10-day intake of radon, 43 patients were united into the control group with no pathological changes in periodontal tissue however. Inhalation and rinsing with radon-containing water causes a decrease in LDH levels in the oral cavity. In patients with mild severity it decreased by 1.29 times, and with moderate severity - by 1.16 times in the main group. The difference is statistically significant (p<0.01). which leads to a decrease in oxidative processes in the oral fluid and the restoration of the fermentation spectrum. As it is known, lactate hydrogenase is an indicator of anaerobic processes and, amylase change and the oral cavity PH, as well as the development of different forms of severity of periodontitis. In our case, the treatment with Tskaltubo water as an antioxidant medicine levels all these processes. Only in case of rinses with water of Tskaltubo, these changes are less pronounced, and in case of both inhalation and rinses they are more pronounced.
对20至40岁患有各种形式牙周炎的132名患者口腔中的临床和生化过程进行研究,确定了口腔整个生化谱的变化。主要组中患有轻度至中度牙周炎的类似随访患者被分为三组,在10天内摄入氡气,然而,43名患者被归入对照组,其牙周组织无病理变化。吸入和用含氡水冲洗会导致口腔中乳酸脱氢酶(LDH)水平降低。在主要组中,轻度严重程度的患者该水平降低了1.29倍,中度严重程度的患者降低了1.16倍。差异具有统计学意义(p<0.01),这导致口腔液中氧化过程减少以及发酵谱恢复。众所周知,乳酸脱氢酶是厌氧过程的指标,以及淀粉酶变化、口腔pH值以及不同严重程度牙周炎的发展情况。在我们的案例中,用茨卡图博水作为抗氧化药物进行治疗可使所有这些过程趋于正常。仅在用茨卡图博水冲洗的情况下,这些变化不太明显,而在吸入和冲洗两者皆有的情况下,变化更明显。