因卵巢癌转移导致的胆肠内瘘罕见病例报告。

Medstar Washington Hospital Center, Washington, DC, USA.

Augusta University Medical Center, Medical College of Georgia, Augusta, GA, USA.

J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620934680. doi: 10.1177/2324709620934680.

Choledochoduodenal fistula (CDF) is an abnormal communication between the common bile duct and the duodenum. It accounts for about 5% to 25% of the total biliary fistulas and is usually due to a perforated duodenal ulcer, choledocholithiasis, and complications secondary to tuberculosis or could be iatrogenic. Primary intrabilliary tumors usually cause obstructive jaundice and rarely biliary metastasis arising from other organs like colon, breast, and lungs can cause obstructive jaundice. There has been a case report of metastasis from ovarian cancer to the major papilla of the duodenum but no reported cases of it causing a CDF. We report a rare case of an 83-year-old female with ovarian cancer who developed a metastatic lesion to the duodenum eventually resulting in a CDF.

胆总管十二指肠瘘（CDF）是胆总管与十二指肠之间的异常通道。它占总胆瘘的 5%至 25%，通常是由于十二指肠溃疡穿孔、胆总管结石以及结核或医源性并发症引起的。原发性胆管内肿瘤通常导致阻塞性黄疸，而来自结肠、乳腺和肺部等其他器官的罕见胆道转移也可引起阻塞性黄疸。有一例报告称，卵巢癌转移至十二指肠主乳头，但没有报告称其导致 CDF。我们报告了一例罕见的病例，一名 83 岁女性患有卵巢癌，发展为十二指肠转移病变，最终导致 CDF。