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CT引导与MR引导的立体定向体部放疗的时间驱动作业成本法比较

Time-Driven Activity-Based Costing Comparison of CT-Guided Versus MR-Guided SBRT.

作者信息

Parikh Neil R, Lee Percy P, Raman Steven S, Cao Minsong, Lamb James, Tyran Marguerite, Chin Walter, Gilchrist Travis, Agazaryan Nzhde, Mittauer Kathryn, Steinberg Michael L, Raldow Ann C

机构信息

Department of Radiation Oncology, University of California, Los Angeles, CA.

Department of Interventional Radiology, University of California, Los Angeles, CA.

出版信息

JCO Oncol Pract. 2020 Nov;16(11):e1378-e1385. doi: 10.1200/JOP.19.00605. Epub 2020 Jun 15.

Abstract

PURPOSE

Magnetic resonance-guided radiation therapy (MRgRT) has recently become commercially available, offering the opportunity to accurately image and target moving tumors as compared with computed tomography-guided radiation therapy (CTgRT) systems. However, the costs of delivering care with these 2 modalities remain poorly described. With localized unresectable hepatocellular carcinoma as an example, we were able to use time-driven activity-based costing to determine the cost of treatment on linear accelerators with CTgRT compared with MRgRT.

MATERIALS AND METHODS

Process maps, informed via interviews with departmental personnel, were created for each phase of the care cycle. Stereotactic body radiation therapy was delivered at 50 Gy in 5 fractions, either with CTgRT using fiducial placement, deep inspiration breath-hold (DIBH) with real-time position management, and volumetric-modulated arc therapy, or with MRgRT using real-time tumor gating, DIBH, and static-gantry intensity-modulated radiation therapy.

RESULTS

Direct clinical costs were $7,306 for CTgRT and $8,622 for MRgRT comprising personnel costs ($3,752 $3,603), space and equipment costs ($2,912 $4,769), and materials costs ($642 $250). Increased MRgRT costs may be mitigated by forgoing CT simulation ($322 saved) or shortening treatment to 3 fractions ($1,815 saved). Conversely, adaptive treatment with MRgRT would result in an increase in cost of $529 per adaptive treatment.

CONCLUSION

MRgRT offers real-time image guidance, avoidance of fiducial placement, and ability to use adaptive treatments; however, it is 18% more expensive than CTgRT under baseline assumptions. Future studies that elucidate the magnitude of potential clinical benefits of MRgRT are warranted to clarify the value of using this technology.

摘要

目的

磁共振引导放射治疗(MRgRT)最近已投入商业使用,与计算机断层扫描引导放射治疗(CTgRT)系统相比,它提供了对移动肿瘤进行精确成像和靶向的机会。然而,使用这两种方式提供护理的成本仍描述甚少。以局部不可切除的肝细胞癌为例,我们能够使用基于时间驱动作业成本法来确定与MRgRT相比,在配备CTgRT的直线加速器上进行治疗的成本。

材料与方法

通过与部门人员访谈获取信息,为护理周期的每个阶段创建流程图。立体定向体部放射治疗以50 Gy分5次进行,要么采用CTgRT,通过放置基准标记、深吸气屏气(DIBH)结合实时位置管理以及容积调强弧形放疗,要么采用MRgRT,通过实时肿瘤门控、DIBH和静态机架调强放射治疗。

结果

CTgRT的直接临床成本为7306美元,MRgRT为8622美元,包括人员成本(3752美元 3603美元)、空间和设备成本(2912美元 4769美元)以及材料成本(642美元 250美元)。放弃CT模拟(节省322美元)或缩短治疗至3次分割(节省1815美元)可减轻MRgRT成本的增加。相反,采用MRgRT进行适应性治疗将导致每次适应性治疗成本增加529美元。

结论

MRgRT提供实时图像引导、无需放置基准标记以及进行适应性治疗的能力;然而,在基线假设下,它比CTgRT贵18%。有必要开展进一步研究以阐明MRgRT潜在临床益处的程度,从而明确使用该技术的价值。

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