Tanaka T, Suwa S, Yokoya S, Hibi I
Endocrine Research Laboratory, National Children's Medical Research Centre, Tokyo, Japan.
Acta Paediatr Scand Suppl. 1988;347:25-9.
Linear growth was analysed in 438 boys and 483 girls aged from 6 years to 17 years. Annual records of each subject were fitted by using a cubic spline function. Parameters characterizing the growth process, such as peak height velocity (PHV), age at PHV, and age at onset of the pubertal growth spurt (PGS), were calculated directly from the estimated curves. The mean age at PHV was 11.2 years in girls and 13.0 years in boys. The mean PHV was 8.7 cm/year in girls and 10.3 cm/year in boys. Age at PHV showed a significant negative correlation with PHV and total pubertal gain, and a significant positive correlation with height at onset of the PGS, age at onset of the PGS and height at PHV. When subjects were divided into three groups (early, average and late pubertal maturation) according to the age at PHV, no significant difference in mean final height was seen between these groups, though a significant difference in height was observed at 6 years of age. When the results were adjusted for the difference in height at 6 years, the age at PHV showed a significant positive correlation with final height. It is concluded that age at PHV influences the final height.
对438名6至17岁的男孩和483名6至17岁的女孩的线性生长情况进行了分析。利用三次样条函数拟合每个受试者的年度记录。直接从估计曲线计算出表征生长过程的参数,如身高峰值速度(PHV)、PHV时的年龄以及青春期生长突增(PGS)开始时的年龄。女孩PHV的平均年龄为11.2岁,男孩为13.0岁。女孩的平均PHV为8.7厘米/年,男孩为10.3厘米/年。PHV时的年龄与PHV和青春期总增长呈显著负相关,与PGS开始时的身高、PGS开始时的年龄以及PHV时的身高呈显著正相关。根据PHV时的年龄将受试者分为三组(青春期早熟、平均和晚熟),尽管在6岁时观察到身高有显著差异,但这些组之间的平均最终身高没有显著差异。当对6岁时的身高差异进行校正后,PHV时的年龄与最终身高呈显著正相关。得出的结论是,PHV时的年龄会影响最终身高。