Department of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Department of Laboratory Sciences, School of Allied Medical Sciences, Ilam University of Medical sciences, Ilam, Iran.
Infect Disord Drug Targets. 2021;21(3):339-357. doi: 10.2174/1871526520666200616145150.
Some fungal species of the genera Aspergillus, Penicillium, and Fusarium secretes toxic metabolites known as mycotoxins, have become a global concern that is toxic to different species of animals and humans. Biological mycotoxins detoxification has been studied by researchers around the world as a new strategy for mycotoxin removal. Bacteria, fungi, yeast, molds, and protozoa are the main living organisms appropriate for the mycotoxin detoxification. Enzymatic and degradation sorptions are the main mechanisms involved in microbiological detoxification of mycotoxins. Regardless of the method used, proper management tools that consist of before-harvest prevention and after-harvest detoxification are required. Here, in this review, we focus on the microbiological detoxification and mechanisms involved in the decontamination of mycotoxins.
一些属于曲霉属、青霉属和镰刀菌属的真菌会分泌有毒的代谢物，称为霉菌毒素，这些毒素对不同种类的动物和人类都有毒性，已成为全球关注的问题。生物霉菌毒素解毒已成为世界各地研究人员研究的一个新策略，以去除霉菌毒素。细菌、真菌、酵母、霉菌和原生动物是适合霉菌毒素解毒的主要生物。酶和降解吸附是微生物解毒霉菌毒素的主要机制。无论使用哪种方法，都需要包含收获前预防和收获后解毒的适当管理工具。在这里，我们重点介绍微生物解毒和脱除霉菌毒素的机制。
