Ben Taheur Fadia, Kouidhi Bochra, Al Qurashi Yasir Mohammed A, Ben Salah-Abbès Jalila, Chaieb Kamel
Laboratory of Analysis, Treatment and Valorization of Environmental Pollutants and Products, Faculty of Pharmacy, Monastir University, Tunisia.
College of Applied Medical Sciences, Medical Laboratory Department, Yanbu el Bahr, Taibah University, Saudi Arabia.
Toxicon. 2019 Mar 15;160:12-22. doi: 10.1016/j.toxicon.2019.02.001. Epub 2019 Feb 15.
Mycotoxins are secondary metabolites produced by various toxigenic fungi belonging to the genera Aspergillus, Fusarium and Penicillium. They have mutagenic, teratogenic, carcinogenic, immunosuppressive and endocrine disrupting effects on both humans and animals. The ubiquitous occurrence and heat stability of these mycotoxins during food and feed processing pose serious health problems in human and animals. Therefore successful biotechnological detoxification tools are in great demand. Recently, the use of bacteria, yeast, moulds and enzymes to mitigate/bind or biodegrade various mycotoxins is a novel strategy used for mycotoxins removal. In this review, recent development in biological control of mycotoxins removal and detoxification will be discussed.
霉菌毒素是由曲霉属、镰刀菌属和青霉属等多种产毒真菌产生的次生代谢产物。它们对人类和动物具有诱变、致畸、致癌、免疫抑制和内分泌干扰作用。这些霉菌毒素在食品和饲料加工过程中普遍存在且具有热稳定性，给人类和动物带来了严重的健康问题。因此，迫切需要成功的生物技术解毒工具。最近，利用细菌、酵母、霉菌和酶来减轻/结合或生物降解各种霉菌毒素是一种用于去除霉菌毒素的新策略。在这篇综述中，将讨论霉菌毒素去除和解毒生物控制方面的最新进展。
