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自体移植成功矫正鱼鳞癣相关的外翻。

Successful correction of ichthyosis-related ectropion by autografts.

机构信息

Department of Ophthalmology, Istanbul Medeniyet University School of Medicine, Istanbul, Turkey.

Department of Ophthalmology, Sultanbeyli State Hospital, Istanbul, Turkey.

出版信息

Dermatol Ther. 2020 Nov;33(6):e13851. doi: 10.1111/dth.13851. Epub 2020 Jul 9.

DOI:10.1111/dth.13851
PMID:32543709
Abstract

Ectropion is a rather frequent complication of ichthyosis with negative functional and esthetic impact. Lid surgery can provide significant improvement. We report on a series of four ichthyosis patients with ongoing bilateral eye problems despite intense medical treatment (mean age 27.8 ± 14.1 years). All patients suffered from lagophthalmos. Two of the patients had only lower lid ectropion. In two of the patients' ectropion was forming on the upper lid in addition to the lower lid when closing the eye. In three of four patients, ectropion was repaired by skin grafts from the supraclavicular region. In a child with lower and upper lid ectropion prepuce was used for repair surgery. At the end of the follow-up period of about 23.0 ± 12.7 months, none of the patients revealed lagophthalmos or corneal exposure. No intraoperative or postoperative complications have been observed in our patients. Ichthyosis patients with ectropion resistant to medical treatment, benefit from surgical treatment with full layer autografts. In boys, prepuce can be successfully used as autograft.

摘要

外翻是鱼鳞病常见的并发症,对功能和美观有负面影响。眼睑手术可以显著改善。我们报告了 4 例鱼鳞病患者,尽管接受了强化治疗(平均年龄 27.8 ± 14.1 岁),但仍持续存在双侧眼部问题。所有患者均存在睑裂闭合不全。其中 2 例患者只有下眼睑外翻。在 2 例患者中,当闭眼时,上眼睑除了下眼睑外还形成了外翻。在 4 例患者中的 3 例中,采用锁骨上区域的皮片移植修复了外翻。对于患有下眼睑和上眼睑外翻的儿童,采用包皮进行修复手术。在随访期结束时约 23.0 ± 12.7 个月时,没有患者出现睑裂闭合不全或角膜暴露。我们的患者没有观察到术中或术后并发症。对药物治疗有抵抗力的外翻鱼鳞病患者受益于全层自体移植物的手术治疗。对于男孩,可以成功地使用包皮作为自体移植物。

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