Department of Neurosurgery, Sir Ganga Ram Hospital, New Delhi, India.
J Neurovirol. 2020 Aug;26(4):615-618. doi: 10.1007/s13365-020-00863-y. Epub 2020 Jun 16.
Nocardia is a Gram-positive, partially acid-fast, catalase-positive, and urease-positive bacterium that grows aerobically. We present an extremely rare case of cauda equina syndrome due to isolated intramedullary Nocardia farcinica infection. A 44-year-old male presented with low backache and gradually progressive weakness in bilateral lower limbs followed by paraplegia. He was found to have a well-defined, sharply demarcated ring-enhancing lesion located from T11-T12 to L3 vertebral body. He underwent laminectomy and decompression. The histopathological examination revealed a Gram-positive filamentous organism that looks like Nocardia. The culture report was suggestive of Nocardia farcinica. He was then treated with antibiotics and had a remarkable clinical and radiological improvement.
奴卡菌是一种革兰阳性、部分抗酸、过氧化氢酶阳性和脲酶阳性的需氧细菌。我们报告一例极为罕见的胸腰椎髓内奴卡菌感染致马尾综合征的病例。一名 44 岁男性因腰痛和逐渐进展的双侧下肢无力，随后出现截瘫而就诊。他被发现有一个界限清楚、明显强化的环形病变，从 T11-T12 椎体到 L3 椎体。他接受了椎板切除术和减压术。组织病理学检查显示革兰阳性丝状病原体，类似于奴卡菌。培养报告提示为星形奴卡菌。随后他接受了抗生素治疗，临床和影像学均有显著改善。
