Valeh Toraj, Ejtahed Hanieh-Sadat, Hasani-Ranjbar Shirin
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Obesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
J Diabetes Metab Disord. 2020 Feb 21;19(1):561-563. doi: 10.1007/s40200-019-00463-6. eCollection 2020 Jun.
The aim of this study was to describe clinical findings in a 45-year-old man with history of two sided cataract surgery, convulsions and progressive memory impairment.
The patient presented to the neurology department because of having progressive memory impairment over the past two years. After taking necessary examinations the patient was referred to the endocrine center because of hypocalcemia in laboratory tests. Brain CT scan and MRI was also done.
Brain CT scan of patient showed extensive and symmetric calcification of basal ganglia, thalami and cerebellum. On Brain MRI, abnormal signal foci in the both sided paraventricular regions, basal ganglia and cerebellar hemisphere were depicted. Laboratory investigations were notable for low serum calcium (5.4 mg/dl, reference range: 8.2-11.2), high serum phosphorus (7.6 mg/dl, reference range: 2.7-4.5), vitamin D deficiency (25-OH D3: 14.5 ng/ml) and low parathyroid hormone (IPTH: 3.7 pg/mL, reference range: 10-62).
This patient presented with amnesia which is a rare presentation of hypoparathyroidism.
本研究旨在描述一名45岁男性的临床症状，该患者有双侧白内障手术史、抽搐和进行性记忆障碍。
患者因过去两年出现进行性记忆障碍就诊于神经科。在进行必要检查后，由于实验室检查发现低钙血症，患者被转诊至内分泌中心。同时还进行了脑部CT扫描和MRI检查。
患者脑部CT扫描显示基底节、丘脑和小脑广泛对称钙化。脑部MRI显示双侧脑室旁区域、基底节和小脑半球有异常信号灶。实验室检查结果显示血清钙水平低（5.4mg/dl，参考范围：8.2 - 11.2）、血清磷水平高（7.6mg/dl，参考范围：2.7 - 4.5）、维生素D缺乏（25 - OH D3：14.5ng/ml）以及甲状旁腺激素水平低（IPTH：3.7pg/mL，参考范围：10 - 62）。
该患者表现为失忆，这是甲状旁腺功能减退症的一种罕见表现。
