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急性缺血性卒中的新兴疗法

Emerging therapies in acute ischemic stroke.

作者信息

Liaw Nicholas, Liebeskind David

机构信息

Department of Vascular Neurology, University of California, Los Angeles, 635 Charles E Young Drive South, Suite 225, Los Angeles, California, 90095-7334, USA.

出版信息

F1000Res. 2020 Jun 5;9. doi: 10.12688/f1000research.21100.1. eCollection 2020.

DOI:10.12688/f1000research.21100.1
PMID:32551094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7276937/
Abstract

Thrombolysis and mechanical thrombectomy have revolutionized the care of patients with acute ischemic stroke. The number of patients who can benefit from these treatments continues to increase as new studies demonstrate that not just time since stroke onset but also collateral circulation influences outcome. Technologies such as telestroke, mobile stroke units, and artificial intelligence are playing an increasing role in identifying and treating stroke. Stroke-systems-of-care models continue to streamline the delivery of definitive revascularization in the age of mechanical thrombectomy.

摘要

溶栓和机械取栓彻底改变了急性缺血性脑卒中患者的治疗方式。随着新研究表明,不仅卒中发作后的时间,而且侧支循环也会影响预后,能够从这些治疗中获益的患者数量持续增加。远程卒中、移动卒中单元和人工智能等技术在识别和治疗卒中方面发挥着越来越重要的作用。在机械取栓时代,卒中医疗系统模式继续简化确定性血管重建的实施。

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Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.尼替西农治疗急性缺血性脑卒中的疗效和安全性(ESCAPE-NA1):一项多中心、双盲、随机对照试验。
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Aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion (COMPASS): a multicentre, randomised, open label, blinded outcome, non-inferiority trial.抽吸血栓切除术与支架取栓术作为血管内治疗大动脉闭塞(COMPASS)的一线治疗方法:一项多中心、随机、开放标签、盲法结局、非劣效性试验。
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J Neurointerv Surg. 2019 May;11(5):455-459. doi: 10.1136/neurintsurg-2018-014196. Epub 2018 Sep 27.