Ogun G O, Takure A O, Ezenkwa U S, Chibuzor I N
Department of Pathology, University of Ibadan/University College Hospital, Ibadan Nigeria.
Department of Surgery (Division of Urology), University of Ibadan/ University College Hospital, Ibadan.
J West Afr Coll Surg. 2018 Apr-Jun;8(2):91-104.
Most testicular adnexal tumours are mesenchymal in origin and have a high tendency to be malignant. An earlier study from our centre found 10 cases, all malignant. The present study reviewed and updated testicular adnexal mesenchymal tumours diagnosed at the University College Hospital, Ibadan, Nigeria.
To document the histopathologic spectrum and characteristics of testicular adnexal mesenchymal tumours diagnosed in our centre over a 20 year period and to compare these with earlier studies from our center and other parts of the world.
This was a descriptive retrospective study.
This study was carried out at the Departments of Pathology and Surgery (Urology Division), University of Ibadan/ University College Hospital, Ibadan Nigeria.
All testicular adnexal mesenchymal tumours from the files and records of the Department of Pathology, University College Hospital Ibadan from January 1, 1997 to December 31, 2016 were reviewed. Age, tumour size and histopathologic diagnosis were retrieved. The tumours were re-evaluated, immunohistochemistry was applied where appropriate and the tumours were reclassified histologically using the 2016 World Health Organisation classification of mesenchymal tumours of the spermatic cord and testicular adnexa. Descriptive statistics was applied on the data generated using SPSS version 20.
Twenty-one cases of testicular adnexal mesenchymal tumours were found over the study period. Three (14.3%) were benign and comprised one case each of lipoma, leiomyoma, and fibrous pseudotumour. The remaining 18 (85.7%) cases were malignant. Rhabdomyosarcoma was the commonest tumour seen accounting for 12 (66.7%) of all the sarcomas followed by liposarcoma 3(16.7%). A case each of malignant peripheral nerve sheath tumour, fibrosarcoma and giant cell sarcoma were also documented. The overall mean age of the patients was 25.8±15.2 years with a range of 7-71 years, while the mean age of the patients with rhabdomyosarcoma was 22.0±8.7 years (8-42 years).
The outcome of this study suggests that the incidence of sarcomas of the testicular adnexa might be on the rise compared to previous report from our centre.
大多数睾丸附件肿瘤起源于间叶组织，且具有较高的恶变倾向。我们中心早期的一项研究发现了10例病例，均为恶性。本研究回顾并更新了在尼日利亚伊巴丹大学学院医院诊断的睾丸附件间叶组织肿瘤。
记录我们中心在20年期间诊断的睾丸附件间叶组织肿瘤的组织病理学谱和特征，并将其与我们中心及世界其他地区的早期研究进行比较。
这是一项描述性回顾性研究。
本研究在尼日利亚伊巴丹大学/伊巴丹大学学院医院的病理科和外科（泌尿外科）进行。
回顾了伊巴丹大学学院医院病理科1997年1月1日至2016年12月31日档案和记录中的所有睾丸附件间叶组织肿瘤。获取患者年龄、肿瘤大小和组织病理学诊断信息。对肿瘤进行重新评估，酌情应用免疫组织化学，并根据2016年世界卫生组织精索和睾丸附件间叶组织肿瘤分类对肿瘤进行组织学重新分类。使用SPSS 20版对所产生的数据进行描述性统计。
在研究期间共发现21例睾丸附件间叶组织肿瘤。3例（14.3%）为良性，分别为脂肪瘤、平滑肌瘤和纤维性假瘤各1例。其余18例（85.7%）为恶性。横纹肌肉瘤是最常见的肿瘤，占所有肉瘤的12例（66.7%），其次是脂肪肉瘤3例（16.7%）。还记录了1例恶性外周神经鞘瘤、纤维肉瘤和巨细胞肉瘤。患者的总体平均年龄为25.8±15.2岁，范围为7 - 71岁，而横纹肌肉瘤患者的平均年龄为照22.0±8.7岁（8 - 42岁）。
本研究结果表明，与我们中心之前的报告相比，睾丸附件肉瘤的发病率可能在上升。
