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头颈部手术中基于重症监护病房的术后管理对微血管游离皮瓣重建的价值。

Value of Intensive Care Unit-Based Postoperative Management for Microvascular Free Flap Reconstruction in Head and Neck Surgery.

机构信息

Department of Otolaryngology-Head & Neck Surgery, University of Michigan, Michigan Medicine, Ann Arbor, Michigan, USA.

Department of Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

出版信息

Facial Plast Surg Aesthet Med. 2021 Jan-Feb;23(1):49-53. doi: 10.1089/fpsam.2020.0055. Epub 2020 Jun 18.

Abstract

Although routine postoperative care for microvascular free flap reconstruction typically involves admission to the intensive care unit (ICU), few studies have investigated the effect of postoperative care setting on clinical outcomes and institution cost. To determine the value of non-ICU-based postoperative management for free tissue transfer for head and neck surgery, in terms of clinical outcomes and cost-effectiveness. This is a retrospective cohort study of two groups of adults who underwent vascularized free tissue transfer from October 2013 to October 2017 at an academic tertiary care center and community-based hospital, respectively. Postoperative management differed such that the first group recovered in a protocol-driven non-ICU setting and the second group was cared for in a planned admission to the ICU. A single surgeon performed all tissue harvest and reconstruction at both centers. Descriptive statistics and cost analyses were performed to compare clinical outcomes and total surgical and downstream direct cost to the institution between the two patient groups. Categorical variables were compared using test where appropriate. Among a total of 338 patients who underwent microvascular free flap reconstruction for head and neck surgical defects, there was no significant difference in patient characteristics such as demographics, comorbidities, history of surgical resection, prior free flap, and locoradiation between the postoperative ICU cohort ( = 146) and protocol-driven non-ICU cohort ( = 192). There were 16 patients in the non-ICU group who spent >3 days in the ICU postoperatively secondary to patient comorbidities and patient care priorities. Still, the average ICU length of stay was 7 days (interquartile range [IQR] 6-9 days) for the planned ICU cohort versus 1 day (IQR 0-1) for the non-ICU group ( < 0.00001). There was no difference in operative variables such as donor site, case length, or total length of stay, and postoperative management in the ICU versus non-ICU setting resulted in no significant difference in terms of flap survival, reoperation, readmission, and postoperative complications. However, average cost of care was significantly higher for patients who received ICU-based care versus non-ICU postoperative care. Specifically, room and board were 239% more costly for the planned ICU care group than the non-ICU setting ( < 0.00001). This study demonstrates that postoperative management after vascularized free tissue transfer in a non-ICU setting is equivalent to standard ICU-based management, in terms of clinical outcomes, while being less costly.

摘要

虽然微血管游离皮瓣重建的常规术后护理通常需要入住重症监护病房(ICU),但很少有研究调查术后护理环境对临床结果和机构成本的影响。为了确定非 ICU 为基础的术后管理对头颈外科游离组织转移的价值,从临床结果和成本效益方面进行评估。这是一项回顾性队列研究,纳入了分别于 2013 年 10 月至 2017 年 10 月在学术三级保健中心和社区医院接受血管化游离组织转移的两组成年人。术后管理不同,第一组在以方案为驱动的非 ICU 环境中恢复,第二组则计划入住 ICU。两位外科医生均在两个中心进行所有组织采集和重建。使用描述性统计和成本分析来比较两组患者的临床结果和总手术以及下游直接机构成本。适当情况下使用卡方检验比较分类变量。在总共 338 名接受头颈部手术缺损微血管游离皮瓣重建的患者中,两组患者的特征(如人口统计学、合并症、手术切除史、既往游离皮瓣和局部放疗)无显著差异。ICU 组(n=146)和以方案为驱动的非 ICU 组(n=192)。非 ICU 组中有 16 名患者由于患者合并症和患者护理优先级而在术后 ICU 中住院超过 3 天。尽管如此,计划 ICU 组的平均 ICU 住院时间为 7 天(IQR 6-9 天),而非 ICU 组为 1 天(IQR 0-1)(<0.00001)。在手术变量方面,如供区、手术时长或总住院时长,以及 ICU 与非 ICU 环境下的术后管理方面,皮瓣存活率、再次手术、再入院和术后并发症方面无显著差异。然而,接受 ICU 为基础护理的患者的平均护理成本明显高于接受非 ICU 术后护理的患者。具体来说,计划 ICU 护理组的病房和床位费用比非 ICU 环境高 239%(<0.00001)。本研究表明,在非 ICU 环境下进行血管化游离组织转移后的术后管理与标准 ICU 为基础的管理在临床结果方面相当,同时成本更低。

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