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食管闭锁中食管漏的早期处理:观念的转变。

Early Management of Esophageal Leak in Esophageal Atresia: Changing Paradigms.

机构信息

Clínica Las Condes, Las Condes, Chile.

Hospital Exequiel González Cortes, Santiago de Chile, Chile.

出版信息

J Laparoendosc Adv Surg Tech A. 2020 Aug;30(8):923-926. doi: 10.1089/lap.2020.0099. Epub 2020 Jun 17.

DOI:10.1089/lap.2020.0099
PMID:32552247
Abstract

A leak at the esophageal anastomosis can occur in 10%-20% of cases of esophageal atresia (EA). Thoracoscopic repair is trans-pleural, with the potential development of an empyema. Standard treatment of an anastomotic leak in a stable patient is often nonoperative, which can lead to prolonged parenteral nutrition and hospitalization. Our objective is to show that early thoracoscopic redo anastomosis management is safe and feasible. Retrospective study of a case series of four infants, diagnosed with EA and treated with early thoracoscopic esophageal leak repair between 2013 and 2018. Variables analyzed included age, weight, type of EA, day of leak, surgical approach, time to start feeding, surgical complications, and follow-up. Three patients were type III, and one was type I originally repaired with a thoracoscopic approach. Leaking of the anastomosis was found the second postoperative day in one patient, third day in two patients, and the fifth day in the last one. All were confirmed with an esophagogram. All patients were operated in the first 24 hours after diagnosis by the thoracoscopic approach. The site of leak was found and re-sutured. Patients started feeding between the third and fourth day through a transanastomotic tube, starting oral feeding at the seventh day after an esophagogram did not show a leak. No complications were found. Mean time to complete oral feeding was 10 days. Two patients needed esophageal dilations. Mean time of follow-up has been 33 months. Early thoracoscopic repair of an anastomotic leak can be considered an alternative to the standard nonsurgical management. The early re-suture of the area of leak is a change in paradigm, but it offers the benefits of preservation of the native esophagus, early resumption of enteral feedings, and a shorter length of parental nutrition and hospitalization. IV.

摘要

食管吻合口漏在食管闭锁(EA)病例中发生率为 10%-20%。胸腔镜修复是经胸膜的,可能发展为脓胸。稳定患者吻合口漏的标准治疗通常是非手术的,这可能导致长期肠外营养和住院。我们的目的是表明早期胸腔镜再次吻合术管理是安全可行的。

对 2013 年至 2018 年间接受早期胸腔镜食管漏修复治疗的 4 例婴儿的病例系列进行回顾性研究。分析的变量包括年龄、体重、EA 类型、漏口出现的天数、手术方法、开始喂养的时间、手术并发症和随访。

3 例为 III 型,1 例最初经胸腔镜治疗为 I 型。1 例患者在术后第 2 天发现吻合口漏,2 例患者在术后第 3 天发现吻合口漏,最后 1 例患者在术后第 5 天发现吻合口漏。所有患者均经食管造影证实。所有患者均在诊断后 24 小时内通过胸腔镜手术治疗。发现漏口并重新缝合。患者通过经吻合口管在第 3-4 天开始喂养,在食管造影未显示漏口后第 7 天开始口服喂养。未发现并发症。完全经口喂养的平均时间为 10 天。2 例患者需要食管扩张。平均随访时间为 33 个月。

早期胸腔镜修复吻合口漏可作为标准非手术治疗的替代方法。早期缝合漏口区域是一种观念上的转变,但它具有保留原生食管、早期恢复肠内喂养、缩短肠外营养和住院时间的好处。

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