Department of Ophthalmology, Columbia University Irving Medical Center , New York, NY, USA.
College of Medicine at the State University of New York at Downstate Medical Center , Brooklyn, NY, USA.
Ophthalmic Genet. 2020 Oct;41(5):413-419. doi: 10.1080/13816810.2020.1780619. Epub 2020 Jun 19.
Optical coherence tomography (OCT) is a non-invasive imaging test that provides easily obtainable and highly reproducible cross-sectional images of the retina. Improved modalities of the OCT that are capable of providing high quality images of not only the retina, but also the deeper structures and vasculature have been developed, including swept-source OCTs and OCT angiography.
Review.
The use of OCT in the monitoring of retinitis pigmentosa has been well described and numerous signs of disease progression have been studied. Notably among them are the detection of changes to retinal thickness, the ellipsoid zone, the vasculature on OCT angiography, and cystoid macular edema.
In this review, we discuss the multiple applications of OCT as a tool in the monitoring of retinitis pigmentosa and its potential use as an outcome measurement in current and future therapeutic endeavors.
光学相干断层扫描(OCT)是一种非侵入性成像测试,可以提供视网膜的易于获得且高度可重复的横截面图像。已经开发出了改进的 OCT 模式,不仅能够提供视网膜的高质量图像,还能够提供更深层结构和脉管系统的高质量图像,包括扫频源 OCT 和 OCT 血管造影。
综述。
OCT 在监测色素性视网膜炎中的应用已有很好的描述,并且已经研究了许多疾病进展的迹象。其中值得注意的是检测视网膜厚度、椭圆体带、OCT 血管造影上的血管以及囊样黄斑水肿的变化。
在这篇综述中,我们讨论了 OCT 作为监测色素性视网膜炎的工具的多种应用及其作为当前和未来治疗努力的结果测量的潜在用途。