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青少年阈下抑郁:患病率、临床特征和相关因素的性别差异。

Subthreshold depression in adolescence: Gender differences in prevalence, clinical features, and associated factors.

机构信息

Millennium Nucleus to Improve the Mental Health of Adolescents and Youths (Imhay), Santiago, Chile; Doctorado en Salud Pública, Escuela de Salud Pública, Universidad de Chile, Santiago, Chile; Millennium Institute for Research in Depression and Personality (MIDAP), Santiago, Chile.

Millennium Nucleus to Improve the Mental Health of Adolescents and Youths (Imhay), Santiago, Chile; Millennium Institute for Research in Depression and Personality (MIDAP), Santiago, Chile; Centro de Medicina Reproductiva y Desarrollo Integral del Adolescente (CEMERA), Facultad de Medicina, Universidad de Chile, Santiago, Chile.

出版信息

J Affect Disord. 2020 Jul 1;272:269-276. doi: 10.1016/j.jad.2020.03.111. Epub 2020 Apr 29.

Abstract

BACKGROUND

Subthreshold depression (SD) is an important mental health problem in adolescence given its high prevalence, comorbidity, and functional impairment. However, currently little is known about gender differences of SD in adolescence. The aim of this study was to examine gender differences in prevalence, clinical features, and associated factors in adolescents with subthreshold depressive episode (SDE).

METHODS

The participants were 2,022 adolescents between 9 and 11 grades (49.5% girls, 15.2 years average age) recruited from eight state-subsidized schools located in the northern part of Santiago, Chile. The Patient Health Questionnaire-9 (PHQ-9) was used to assess depressive symptoms. Descriptive statistics, bivariate and multinomial logistic regression analyses were used.

RESULTS

The prevalence of SDE and major depressive episode were 16.5% (95% CI: 14.9-18.2) and 17.7% (95% CI: 16.1-19.4), respectively. Both mental health problems were more prevalent in females (p < 0.001). With regard to SDE, girls displayed a higher rate of depressive mood and sleep problems, while boys had greater anhedonia, problems related with concentration, and psychomotor retardation/agitation. High levels of dysfunctional thoughts and perceived social support were associated with SDE in females and males. Social problem solving and emotion regulation had a differentiated impact on SDE depending on gender.

CONCLUSION

Depressive symptoms and SDE were found to be common health problems among adolescents in Chile. SDE had major gender differences in terms of prevalence, clinical features, and associated factors. These differences should be considered in the development of preventive and early interventions.

摘要

背景

阈下抑郁(SD)是青少年中一个重要的心理健康问题,因为它的高患病率、共病和功能障碍。然而,目前对于青春期 SD 的性别差异知之甚少。本研究旨在探讨阈下抑郁发作(SDE)青少年中性别差异的患病率、临床特征和相关因素。

方法

参与者为来自智利圣地亚哥北部的八所政府资助学校的 9 至 11 年级的 2022 名青少年(49.5%为女生,平均年龄为 15.2 岁)。使用患者健康问卷-9(PHQ-9)评估抑郁症状。采用描述性统计、双变量和多项逻辑回归分析。

结果

SDE 和重度抑郁发作的患病率分别为 16.5%(95%CI:14.9-18.2)和 17.7%(95%CI:16.1-19.4)。这两种心理健康问题在女性中更为普遍(p<0.001)。对于 SDE,女孩表现出更高的抑郁情绪和睡眠问题,而男孩则表现出更大的快感缺失、与注意力相关的问题、精神运动迟缓和躁动。高水平的功能失调思维和感知到的社会支持与女性和男性的 SDE 相关。社会问题解决和情绪调节对 SDE 的影响因性别而异。

结论

智利青少年中常见的健康问题是抑郁症状和 SDE。SDE 在患病率、临床特征和相关因素方面存在明显的性别差异。在制定预防和早期干预措施时,应考虑这些差异。

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