Faculty of Psychology, Universidad de Talca, Chile.; Millennium Nucleus to Improve the Mental Health of Adolescents and Youths, Imhay.
Faculty of Psychology, Universidad de Talca, Chile.
J Affect Disord. 2020 Jul 1;272:371-379. doi: 10.1016/j.jad.2020.04.004. Epub 2020 May 7.
A better understanding of the specific contribution of risk factors to suicidal behavior could arise from analyzing suicidal ideation (SI) in clinical samples, and comparing single versus multiple suicide attempters through contemporary methods allowing complex and dynamical analyses of multiple and simultaneously interacting suicide risk factors.
We explored associations among suicidal ideation (SI), affect lability and other suicide risk factors in 323 suicidal attempters diagnosed with major depressive disorder (MDD). We analyzed the network structure and centrality of the total sample, and compared single versus multiple attempters and subjects with low and high suicidal ideation.
SI was connected with anxiety (trait) and hopelessness. Central nodes for global and specific groups were affect lability (from anxiety to depression), anxiety as a trait, and harm avoidance. We observed some specific differences between clinical profiles of repeaters and non-repeaters and significant network density between high and low SI.
Because our cross-sectional design, we cannot establish casual relationships among variables. We only examined associations at group level but not at single subject level.
Affect lability (mainly the shifts from anxiety to depression) and trait anxiety were central in each estimated network. These symptoms might be suitable targets for early detecting and treating suicidal patients.
通过分析临床样本中的自杀意念,并通过允许对多个同时相互作用的自杀风险因素进行复杂和动态分析的现代方法比较单一和多次自杀企图者,可能会更好地了解风险因素对自杀行为的具体贡献。
我们在 323 名被诊断患有重度抑郁症(MDD)的自杀企图者中探讨了自杀意念(SI),情绪不稳定与其他自杀风险因素之间的关联。我们分析了总样本的网络结构和中心性,并比较了单次与多次企图者以及自杀意念程度低和高的患者。
SI 与焦虑(特质)和绝望感有关。全局和特定组的中心节点是情绪不稳定(从焦虑到抑郁),焦虑作为特质和回避伤害。我们观察到重复者和非重复者的临床特征之间存在一些特定差异,并且在高和低 SI 之间存在显著的网络密度。
由于我们的横断面设计,我们无法在变量之间建立因果关系。我们仅在群体水平上检查了关联,而没有在单个患者水平上检查。
情绪不稳定(主要是从焦虑到抑郁的转变)和特质焦虑是每个估计网络中的中心。这些症状可能适合作为早期发现和治疗自杀患者的目标。