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当完全取消共付额时,药物使用和支出会发生什么变化?来自加拿大省级公共药物计划的证据。

What happens to drug use and expenditure when cost sharing is completely removed? Evidence from a Canadian provincial public drug plan.

机构信息

The University of British Columbia, Centre for Health Services and Policy Research, School of Population and Public Health, 2206 E Mall, Vancouver BC V6T1Z3, Canada; Centre for Clinical Epidemiology and Evaluation, The University of British Columbia, Vancouver, Canada; The Centre for Health Economics Research and Evaluation, University of Technology, Sydney. Level 2, Building 5D, 1-59 Quay Street, Haymarket NSW 2000 Australia; The University of Sydney, Menzies Centre for Health Policy, School of Public Health, Faculty of Medicine and Health, D17 Charles Perkins Centre, Sydney 2006, NSW, Australia.

The University of British Columbia, Centre for Health Services and Policy Research, School of Population and Public Health, 2206 E Mall, Vancouver BC V6T1Z3, Canada.

出版信息

Health Policy. 2020 Sep;124(9):977-983. doi: 10.1016/j.healthpol.2020.05.001. Epub 2020 May 23.

Abstract

OBJECTIVES

The role of cost-sharing for medicines is under active policy discussion, including in proposals for value-based insurance design. To inform this debate, we estimated the impact of completely removing cost-sharing on medication use and expenditure using a quasi-experimental approach.

METHODS

Fair PharmaCare, British Columbia's income-based public drug plan, includes a household out-of-pocket limit. Therefore, when one household member starts a long-term high-cost drug surpassing this maximum, cost-sharing is completely removed for other family members. We used an interrupted time series design to estimate monthly prescriptions and expenditures of other household members, 24 months before and after cost-sharing removal.

RESULTS

We studied 2191 household members newly free of cost-sharing requirements, most of whom had lower incomes. R emoving cost-sharing increased the level of drug expenditure and prescription numbers by 16 and 19%, respectively (i.e. $2659.43 (95%$1507.27-$3811.59, p < 0.001); 50.0 (95%CI 25.1-74.9, p < 0.001)) relative to prior expenditures and utilization without changing pre-existing trends. Much of this change was driven by 533 individuals initiating medication for the first time after cost-sharing removal. This initiation substantially increased average expenditure, especially for antiviral agents.

CONCLUSIONS

Completely removing cost-sharing, independent of health status, significantly increased medication use and expenditure particularly due to medicine initiation by new users. While costs may be preventing use, the appropriateness of additional use, especially among new users, is unclear.

摘要

目的

药品共付的作用是当前政策讨论的焦点,包括在基于价值的保险设计方案中。为了为这场辩论提供信息,我们使用准实验方法来估计完全取消药品共付对用药和支出的影响。

方法

不列颠哥伦比亚省的基于收入的公共药品计划“公平药品福利”(Fair PharmaCare)包含家庭自付额上限。因此,当一个家庭成员开始使用一种长期高成本药物且超过这个最高额时,其他家庭成员的共付额将被完全免除。我们使用中断时间序列设计来估计 24 个月内共付额取消前后其他家庭成员的每月处方和支出。

结果

我们研究了 2191 名新免除共付要求的家庭成员,他们中的大多数收入较低。取消共付额使药物支出和处方数量分别增加了 16%和 19%(即 2659.43 美元(95%置信区间 1507.27 美元至 3811.59 美元,p < 0.001);50.0(95%CI 25.1 至 74.9,p < 0.001)),而不会改变之前的趋势。这种变化主要是由 533 名在取消共付额后首次开始用药的人驱动的。这种起始大大增加了平均支出,特别是抗病毒药物。

结论

完全取消共付额,而不考虑健康状况,显著增加了用药和支出,特别是由于新用户开始用药。虽然成本可能会阻止用药,但额外用药的合理性,特别是在新用户中,尚不清楚。

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