Sacco Guillaume, Brière Olivier, Asfar Marine, Guérin Olivier, Berrut Gilles, Annweiler Cédric
Département de gériatrie et Centre Mémoire Ressources Recherche, Centre de recherche sur l'autonomie et la longévité, Centre hospitalier universitaire, Angers, France, UPRES EA 4638, Université d'Angers, Angers, France.
Département de gériatrie et Centre Mémoire Ressources Recherche, Centre de recherche sur l'autonomie et la longévité, Centre hospitalier universitaire, Angers, France.
Geriatr Psychol Neuropsychiatr Vieil. 2020 Jun 1;18(2):135-140. doi: 10.1684/pnv.2020.0863.
The COVID-19 pandemic is particularly severe in older adults. Our objective was to identify, from international literature, the most common symptoms met in older adults infected with the SARS-CoV-2 virus. This systematic review of the literature was conducted using MEDLINE from December 1, 2019 to April 13, 2020. The analysis of methodological quality used a method dedicated to case series and case reports. Out of 260 articles initially identified, only two studies were finally included in the qualitative analysis. The mean age was relatively low, between 71 and 74 years on average. The symptoms of COVID-19 were as follows: fever, dry cough, dyspnea, asthenia, anorexia, chest tightness, diarrhea, and to a lesser extent myalgia, pharyngitis, nausea, dizziness, headache, abdominal pain and finally vomiting. Lymphopenia was found in the complete blood count. In conclusion, this systematic review of the international literature reveals a lack of data about the semiology of COVID-19 in older adults, especially in the frail oldest-old ones who commonly define the geriatric population. The national survey conducted by the French Society of Geriatrics and Gerontology will help fill this semiological gap.
新型冠状病毒肺炎疫情在老年人中尤为严重。我们的目标是从国际文献中确定感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒的老年人中最常见的症状。本系统文献综述使用MEDLINE数据库，检索时间为2019年12月1日至2020年4月13日。方法学质量分析采用了专门针对病例系列和病例报告的方法。在最初确定的260篇文章中，最终只有两项研究纳入了定性分析。平均年龄相对较低，平均在71至74岁之间。新型冠状病毒肺炎的症状如下：发热、干咳、呼吸困难、乏力、厌食、胸闷、腹泻，以及程度较轻的肌痛、咽炎、恶心、头晕、头痛、腹痛，最后是呕吐。全血细胞计数显示淋巴细胞减少。总之，对国际文献的这项系统综述表明，缺乏关于老年人新型冠状病毒肺炎症状学的数据，尤其是在通常构成老年人群体的体弱的高龄老人中。法国老年医学和老年学协会进行的全国性调查将有助于填补这一症状学空白。
