Department of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria.
Siemens Healthcare GmbH, Henkestraße 127, 91052, Erlangen, Germany.
Eur Radiol. 2020 Nov;30(11):6014-6021. doi: 10.1007/s00330-020-06996-2. Epub 2020 Jun 18.
To evaluate magnetic resonance cholangiopancreatography (MRCP) with compressed sensing (CS) for the assessment of branch duct intraductal papillary mucinous neoplasm (BD-IPMN) of the pancreas. For this purpose, conventional navigator-triggered (NT) sampling perfection with application-optimized contrast using different flip angle evolutions (SPACE) MRCP was compared with various CS-SPACE-MRCP sequences in a clinical setting.
A total of 41 patients (14 male, 27 female, mean age 68 years) underwent 1.5-T MRCP for the evaluation of BD-IPMN. The MRCP protocol consisted of the following sequences: conventional NT-SPACE-MRCP, CS-SPACE-MRCP with long (BHL, 17 s) and short single breath-hold (BHS, 8 s), and NT-CS-SPACE-MRCP. Two board-certified radiologists evaluated image quality, duct sharpness, duct visualization, lesion conspicuity, confidence, and communication with the main pancreatic duct in consensus using a 5-point scale (1-5), with higher scores indicating better quality/delineation/confidence. Maximum intensity projection reconstructions and originally acquired data were used for evaluation. Wilcoxon signed-rank test was used to compare the intra-individual difference between sequences.
BHS-CS-SPACE-MRCP had the highest scores for image quality (3.85 ± 0.79), duct sharpness (3.81 ± 1.05), and duct visualization (3.81 ± 1.01). There was a significant difference compared with NT-CS-SPACE-MRCP (p < 0.05) but no significant difference to the standard NT-SPACE-MRCP (p > 0.05). Concerning diagnostic quality, BHS-CS-SPACE-MRCP had the highest scores in lesion conspicuity (3.95 ± 0.92), confidence (4.12 ± 1.08), and communication (3.8 ± 1.06), significantly higher compared with NT-SPACE-MRCP, BHL-SPACE-MRCP, and NT-CS-SPACE-MRCP (p = <0.05).
MRCP with CS 3D SPACE for the evaluation of BD-IPMN at 1.5 T provides the best results using a short breath-hold sequence. This approach is feasible and an excellent alternative to standard NT 3D MRCP sequences.
• 1.5-T MRCP with compressed sensing for the evaluation of branch duct IPMN is a feasible method. • Short breath-hold sequences provide the best results for this purpose.
评估磁共振胰胆管成像（MRCP）与压缩感知（CS）在胰腺分支胰管内乳头状黏液性肿瘤（BD-IPMN）评估中的应用。为此，在临床环境中比较了常规导航触发（NT）采样完善与应用优化对比剂的不同翻转角演化（SPACE）MRCP 与各种 CS-SPACE-MRCP 序列。
共 41 例患者（男 14 例，女 27 例，平均年龄 68 岁）接受 1.5-T MRCP 检查以评估 BD-IPMN。MRCP 方案包括以下序列：常规 NT-SPACE-MRCP、长（BHL，17 s）和短单次屏气（BHS，8 s）CS-SPACE-MRCP 以及 NT-CS-SPACE-MRCP。两名具有董事会认证的放射科医生使用 5 分制（1-5）对共识图像质量、导管清晰度、导管可视化、病变显影、信心和与主胰管的沟通进行评分，评分越高表示质量/描绘/信心越好。使用最大强度投影重建和原始采集数据进行评估。使用 Wilcoxon 符号秩检验比较序列之间的个体内差异。
BHS-CS-SPACE-MRCP 的图像质量（3.85±0.79）、导管清晰度（3.81±1.05）和导管可视化（3.81±1.01）评分最高。与 NT-CS-SPACE-MRCP 相比，差异有统计学意义（p＜0.05），但与标准 NT-SPACE-MRCP 相比，差异无统计学意义（p＞0.05）。在诊断质量方面，BHS-CS-SPACE-MRCP 在病变显影（3.95±0.92）、信心（4.12±1.08）和沟通（3.8±1.06）方面的评分最高，与 NT-SPACE-MRCP、BHL-SPACE-MRCP 和 NT-CS-SPACE-MRCP 相比，差异有统计学意义（p＜0.05）。
1.5-T 磁共振胰胆管成像（MRCP）结合 CS 3D SPACE 可在 1.5 T 下对胰腺分支胰管内乳头状黏液性肿瘤（BD-IPMN）进行评估，使用短呼吸暂停序列可获得最佳结果。该方法可行，是标准 NT 3D MRCP 序列的极好替代方法。
