Kamel Sarah I, Belair Jeffrey A, Hegazi Tarek M, Halpern Ethan J, Desai Vishal, Morrison William B, Zoga Adam C
Department of Musculoskeletal Radiology, Thomas Jefferson University Hospital, Main Building 1090, Philadelphia, PA, 19107, USA.
Department of Radiology, Imam Abdulrahman Bin Faisal University, College of Medicine, Dammam, Saudi Arabia.
Skeletal Radiol. 2020 Dec;49(12):1977-1985. doi: 10.1007/s00256-020-03503-y. Epub 2020 Jun 19.
To provide a novel MRI classification system for the symptomatic type II os naviculare by creating a standardized grading of associated bone marrow edema (BME) and correlating with patient symptoms.
BME was classified on an ordinal scale: grade 1, faint signal immediately adjacent to the synchondrosis; grade 2, intermediate signal within the os and navicular tuberosity without extending to the navicular body; grade 3, intense signal extending to the navicular body. BME on 59 MRIs was independently graded by three radiologists. Inter- and intra-observer agreement was analyzed using intraclass correlation coefficient. Univariate and multivariate analyses assessed for patient and imaging characteristics predictive of subjective pain score. A cohort of 82 patients without BME represented a control group.
Inter-observer agreement of BME grade was 0.95 (CI 0.93-0.97) and intra-observer was 0.92 (CI 0.87-0.96), indicating excellent agreement. In patients with BME, predictors of more severe pain were longer duration of pain (p = 0.02) and presence of soft tissue edema overlying the os naviculare (p < 0.001). One hundred percent of subjects with BME localized their pain to the medial midfoot (59/59) versus 25.6% (21/82) of controls (p < 0.001).
This novel grading system provides reliable quantification of BME associated with os naviculare, which is a specific cause of medial foot/ankle pain. Early diagnosis is important as pain severity worsens with longer duration of symptoms. Pain severity is correlated with soft tissue edema overlying the os, which may be secondary to extrinsic compression, reactive to biomechanical stress, or reflect direct trauma.
通过创建相关骨髓水肿(BME)的标准化分级并与患者症状相关联,为有症状的II型舟状骨提供一种新的MRI分类系统。
BME按顺序量表分类:1级,紧邻软骨结合处的微弱信号;2级,舟状骨和舟状结节内的中等信号,未延伸至舟状骨体;3级,强烈信号延伸至舟状骨体。59例MRI上的BME由三位放射科医生独立分级。使用组内相关系数分析观察者间和观察者内的一致性。单因素和多因素分析评估预测主观疼痛评分的患者和影像学特征。82例无BME的患者组成一个对照组。
BME分级的观察者间一致性为0.95(CI 0.93 - 0.97),观察者内一致性为0.92(CI 0.87 - 0.96),表明一致性极佳。在有BME的患者中,疼痛更严重的预测因素是疼痛持续时间更长(p = 0.02)以及舟状骨上方存在软组织水肿(p < 0.001)。100%有BME的受试者将疼痛定位在内侧中足(59/59),而对照组为25.6%(21/82)(p < 0.001)。
这种新的分级系统为与舟状骨相关的BME提供了可靠的量化,舟状骨是足内侧/踝关节疼痛的一个特定原因。早期诊断很重要,因为疼痛严重程度会随着症状持续时间延长而加重。疼痛严重程度与舟状骨上方的软组织水肿相关,这可能继发于外部压迫、对生物力学应力的反应或反映直接创伤。