Frendl Daniel M, Epstein Mara M, Fouayzi Hassan, Krajenta Richard, Rybicki Benjamin A, Sokoloff Mitchell H
Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
Cancer Causes Control. 2020 Sep;31(9):861-867. doi: 10.1007/s10552-020-01324-x. Epub 2020 Jun 17.
This study describes longitudinal trends in the use of prostate-specific antigen (PSA)-based testing in two geographically distinct healthcare systems following the 2011 US Preventive Services Task Force (USPSTF) recommendations against routine PSA screening.
We analyzed population-based health claims data from 253,139 men aged 40-80 who were enrolled at two US healthcare systems. We assessed trends in the percentage of eligible men receiving ≥ 1 PSA test per year by time period (2000-2008, 2009-2011, 2012-2014), age (40-54, 55-69, 70-80), and race (white, black, other, unknown), and conducted a joinpoint regression analysis.
Men aged 55-69 and 70-80 years of all races had similar use of PSA testing between 2000 and 2011, ranging between 47 and 56% of eligible men by year, while only 22-26% of men aged 40-54 had a PSA test per year during this period. Overall, the percentage of men receiving at least one PSA test per year decreased by 26% between 2009-2011 and 2012-2014, with similar trends across race and age groups. PSA testing declined significantly after 2011 (annual percent change = - 11.28).
Following the 2011 USPSTF recommendations against routine PSA screening, declines in PSA testing were observed among men of all races and across all age groups in two large US healthcare systems.
本研究描述了2011年美国预防服务工作组（USPSTF）建议反对常规前列腺特异性抗原（PSA）筛查后，在两个地理位置不同的医疗保健系统中基于PSA检测的使用情况的纵向趋势。
我们分析了来自美国两个医疗保健系统中登记的253,139名40 - 80岁男性的基于人群的健康索赔数据。我们按时间段（2000 - 2008年、2009 - 2011年、2012 - 2014年）、年龄（40 - 54岁、55 - 69岁、70 - 80岁）和种族（白人、黑人、其他、未知）评估了每年接受≥1次PSA检测的符合条件男性的百分比趋势，并进行了连接点回归分析。
2000年至2011年期间，所有种族的55 - 69岁和70 - 80岁男性PSA检测的使用率相似，每年符合条件的男性中这一比例在47%至56%之间，而在此期间，40 - 54岁男性中每年只有22% - 26%进行了PSA检测。总体而言，2009 - 2011年至2012 - 2014年期间，每年接受至少一次PSA检测的男性百分比下降了26%，不同种族和年龄组的趋势相似。2011年后PSA检测显著下降（年变化百分比 = - 11.28）。
2011年USPSTF建议反对常规PSA筛查后，在美国两个大型医疗保健系统中，所有种族和各年龄组的男性PSA检测率均出现下降。
