2020 年因 COVID-19 大流行而实行的“封锁”期间的癌症诊断率与 2018-2019 年相比：一项来自细胞病理学的审计研究。
Cancer diagnostic rates during the 2020 'lockdown', due to COVID-19 pandemic, compared with the 2018-2019: an audit study from cellular pathology.
机构信息
Anatomic Pathology, Hospital of Macerata, Macerata, Italy.
Department of Histopathology, Warwick Hospital, Warwick, UK.
出版信息
J Clin Pathol. 2021 Mar;74(3):187-189. doi: 10.1136/jclinpath-2020-206833. Epub 2020 Jun 19.
AIMS
We performed an audit to evaluate the impact of the COVID-19 pandemic-related delay in the diagnosis of major cancers at a Pathology Unit of a Secondary Care Hospital Network in Italy.
METHODS
A comparison was made among the number of first cellular pathological diagnoses of malignancy made from the 11th to the 20th week of the years 2018-2020.
RESULTS
Cancer diagnoses fell in 2020 by 39% compared with the average number recorded in 2018 and 2019. Prostate cancer (75%) bladder cancer (66%) and colorectal cancer (CRC; 62%) had the greatest decrease. CRC was identified as carrying a potentially important diagnostic delay.
CONCLUSIONS
For CRC corrective procedures (continuing mass screening tests; patient triage by family physicians; diagnostic procedures alternative to colonoscopy; predictive evaluation on biopsy samples) were advised. Our simple audit model is widely applicable to avoid pandemic-related delay in clinical diagnosis of cancer.
目的
我们进行了一次审核，以评估意大利一家二级保健医院网络的病理学部门在 COVID-19 大流行相关延迟诊断主要癌症方面的影响。
方法
比较了 2018 年至 2020 年第 11 周至第 20 周期间首次进行的恶性肿瘤细胞病理学诊断数量。
结果
与 2018 年和 2019 年的平均记录相比，2020 年癌症诊断减少了 39%。前列腺癌（75%）、膀胱癌（66%）和结直肠癌（CRC；62%）降幅最大。CRC 被确定为存在潜在重要的诊断延迟。
结论
建议对 CRC 采取纠正措施（持续进行大规模筛查试验；家庭医生对患者进行分诊；替代结肠镜检查的诊断程序；对活检样本进行预测性评估）。我们的简单审核模型广泛适用于避免 COVID-19 大流行导致的癌症临床诊断延迟。
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