2019冠状病毒病大流行期间管理HIV相关霍奇金淋巴瘤：病例报告与文献综述

Padurariu-Covit Monica-Daniela, Andreescu Mihaela, Niculet Elena, Plesea-Condratovici Alina, Arbune Manuela

Doctoral School of Biomedical Sciences, Dunarea de Jos University of Galati, 800008 Galati, Romania.

Hematology Department, Emergency County Hospital Sf. Apostol Andrei, 800578 Galati, Romania.

Viruses. 2025 Mar 12;17(3):404. doi: 10.3390/v17030404.

The COVID-19 pandemic delayed the consultation of many patients with specialists. We present the case of a 57-year-old patient with HIV infection, COVID-19 pneumonia, and Hodgkin lymphoma. Discordant immunohistochemistry results from biopsy samples delayed the hematological diagnosis and initiation of oncological therapy. The late diagnosis of HIV infection at the stage of severe immunosuppression, along with advanced Hodgkin lymphoma and COVID-19 co-infection, represents a complex pathogenic triad that is challenging to manage. Healthcare-associated COVID-19 infections pose a significant risk during the pandemic for chronic patients requiring frequent hospital visits.

新冠疫情推迟了许多患者与专科医生的会诊。我们报告了一例57岁的患者，其患有艾滋病毒感染、新冠肺炎和霍奇金淋巴瘤。活检样本免疫组化结果不一致，延迟了血液学诊断和肿瘤治疗的启动。在严重免疫抑制阶段艾滋病毒感染的晚期诊断，以及晚期霍奇金淋巴瘤和新冠病毒合并感染，构成了一个复杂的致病三联征，管理起来具有挑战性。在疫情期间，医疗保健相关的新冠病毒感染对需要频繁住院的慢性病患者构成重大风险。