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甘草酸的药理作用的临床前证据:全面综述。

Preclinical Evidence for the Pharmacological Actions of Glycyrrhizic Acid: A Comprehensive Review.

机构信息

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

RAKCOPS, RAK Medical and Health Sciences University, Ras AL Khaimah, United Arab Emirates.

出版信息

Curr Drug Metab. 2020;21(6):436-465. doi: 10.2174/1389200221666200620204914.

Abstract

Glycyrrhiza glabra L. (Family: Fabaceae) is one of the important traditional medicinal plant used extensively in folk medicine. It is known for its ethnopharmacological value in curing a wide variety of ailments. Glycyrrhizin, an active compound of G. glabra, possesses anti-inflammatory activity due to which it is mostly used in traditional herbal medicine for the treatment and management of chronic diseases. The present review is focused extensively on the pharmacology, pharmacokinetics, toxicology, and potential effects of Glycyrrhizic Acid (GA). A thorough literature survey was conducted to identify various studies that reported on the GA on PubMed, Science Direct and Google Scholar.

摘要

甘草(豆科)是一种重要的传统药用植物,在民间医学中被广泛应用。它以其在治疗多种疾病方面的民族药理学价值而闻名。甘草酸是甘草的一种活性化合物,具有抗炎活性,因此在传统草药中主要用于治疗和管理慢性疾病。本综述广泛关注甘草酸的药理学、药代动力学、毒理学和潜在作用。通过在 PubMed、Science Direct 和 Google Scholar 上进行全面的文献调查,确定了各种报道甘草酸的研究。

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