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经皮椎间孔镜减压联合非融合同种异体骨椎间融合术治疗终末期真空变性椎间盘疾病的可行性研究。

Transforaminal endoscopic decompression and uninstrumented allograft lumbar interbody fusion: A feasibility study in patients with end-stage vacuum degenerative disc disease.

机构信息

Department Orthopaedic Surgery, University of Sao Paulo, Ribeirão Preto, Brazil; Orthopaedic Spine Surgeon, Director of Endoscopic Spine Clinic, Santiago, Chile.

Regional Hospital of High Specialty of Bajío, León, Guanajuato, Mexico.

出版信息

Clin Neurol Neurosurg. 2020 Sep;196:106002. doi: 10.1016/j.clineuro.2020.106002. Epub 2020 Jun 9.

Abstract

OBJECTIVE

The authors investigated the feasibility of a transforaminal endoscopic decompression and un-instrumented lumbar interbody fusion procedures with cancellous bone allograft in patients painful with end-stage degenerative vacuum disc disease.

PATIENTS & METHODS: Twenty-nine patients who underwent endoscopic transforaminal foraminal and lateral recess decompression and direct intraoperative endoscopic visualization of a painful, hollow collapsed, rigid intervertebral disc space were grafted with cancellous allograft chips. In addition to the radiographic assessment of fusion, patients were followed for a minimum of 2 years postoperatively, and clinical outcomes were evaluated with VAS, ODI, and modified MacNab criteria.

RESULTS

At the final follow, mean VAS and ODI scores reduced from 7.34 ± 1.63 and 50.03 ± 10.64 preoperatively to 1.62 ± 1.741 and 6.69 ± 4.294 postoperatively (p < 0.0001). Excellent and Good clinical outcomes, according to Macnab criteria, were obtained in 34.5 % and 62.1 % of patients, respectively. Only one patient had minimal improvement from "Poor" preoperatively to "Fair" postoperatively. This female patient was treated for lumbar disc herniation L5/S1 and had an incomplete fusion at the final follow up. Computed tomography assessment of interbody fusion at the last follow-up showed successful fusion in 91.4 % of patients.

CONCLUSIONS

Un-instrumented interbody fusion by packing a hollow interspace with cancellous bone allograft chips can be considered as an adjunct to endoscopic foraminal and lateral recess decompression in select patients with validated painful, collapsed, and rigid motion segments. It can be safely done in an outpatient setting at a low burden to patients.

摘要

目的

作者研究了在终末期退变性真空椎间盘病患者中,使用经皮椎间孔内窥镜减压和未置内固定的椎间融合术联合松质骨移植物进行治疗的可行性。

患者与方法

29 名患者接受了经皮椎间孔内窥镜下经侧隐窝减压和直接术中内窥镜观察疼痛、空洞塌陷、僵硬的椎间盘间隙,并使用松质骨移植物进行植骨。除了融合的影像学评估外,患者还进行了至少 2 年的术后随访,并通过 VAS、ODI 和改良 MacNab 标准评估临床结果。

结果

在最终随访时,VAS 和 ODI 评分从术前的 7.34 ± 1.63 和 50.03 ± 10.64 分别降至 1.62 ± 1.741 和 6.69 ± 4.294(p < 0.0001)。根据 Macnab 标准,34.5%和 62.1%的患者分别获得了优秀和良好的临床结果。只有 1 名患者从术前的“差”改善为术后的“尚可”。这名女性患者因腰椎间盘 L5/S1 突出症接受治疗,最终随访时融合不完全。最后一次随访时的 CT 评估显示 91.4%的患者椎间融合成功。

结论

在经过验证的疼痛、塌陷和僵硬运动节段的特定患者中,使用松质骨移植物填充空心间隙进行非融合式椎间融合术可以被视为经皮椎间孔内窥镜下经侧隐窝减压术的辅助治疗方法。这种方法可以在门诊环境下安全地进行,对患者的负担较低。

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