Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA, USA.
Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA, USA; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, VA, USA; Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.
Trends Mol Med. 2020 Aug;26(8):715-717. doi: 10.1016/j.molmed.2020.05.006. Epub 2020 Jun 17.
Toll-like receptor (TLR) 2 recognizes and responds to threats early in bacterial infections and can influence the downstream immune response to the host's benefit or detriment. Therapeutic modulation of TLR2 signaling represents an underutilized opportunity to moderate the immune response to infection to promote an improved outcome for the host.
Toll 样受体（TLR）2 在细菌感染的早期识别和响应威胁，并可以影响下游的免疫反应，对宿主有利或有害。TLR2 信号的治疗性调节代表了一个未充分利用的机会，可以调节感染的免疫反应，以促进宿主的更好结果。
