Aljuboori Zaid, Ding Dale, Williams Brian J
Neurological Surgery, University of Louisville School of Medicine, Louisville, USA.
Cureus. 2020 May 18;12(5):e8183. doi: 10.7759/cureus.8183.
The coexistence of brain tumors and unruptured intracranial aneurysms is uncommon, so there is limited data regarding management strategies for these cases. Tumor, aneurysm, and patient factors must be considered in the decision-making process. We present a case of a dural-based left temporal brain tumor with an incidental ipsilateral unruptured anterior cerebral artery (ACA) proximal A1 segment aneurysm. A 56-year-old female presented with progressive headaches and convulsions without focal neurological deficits. Neuroimaging showed a large dural-based left temporal tumor with adjacent vasogenic edema. The patient underwent a cerebral angiography for preoperative tumor embolization, which revealed a small, unruptured intracranial aneurysm arising from the left ACA proximal A1 segment. We performed a left frontotemporal craniotomy for concurrent resection of the dural-based tumor and clipping of the left A1 aneurysm. She elected to proceed, so she underwent a left-sided craniotomy for tumor resection and clipping of the aneurysm. Postoperatively, the patient developed transient, mild right-sided hemiparesis from a left anterior thalamic infarct that resolved before discharge. Follow-up brain magnetic resonance imaging and catheter cerebral angiography showed gross total resection of the tumor and complete aneurysm obliteration, respectively. Patients with dual diagnoses of a brain tumor and intracranial aneurysm can be challenging to manage. When intervention is indicated for each lesion and both can be safely accessed from the same operative approach, contemporaneous surgical treatment of the tumor and aneurysm is reasonable in appropriately selected cases.
脑肿瘤与未破裂颅内动脉瘤并存的情况并不常见,因此关于这些病例的治疗策略的数据有限。在决策过程中必须考虑肿瘤、动脉瘤和患者因素。我们报告一例以硬脑膜为基底的左侧颞叶脑肿瘤,同时偶然发现同侧未破裂的大脑前动脉(ACA)近端A1段动脉瘤。一名56岁女性因进行性头痛和抽搐就诊,无局灶性神经功能缺损。神经影像学检查显示一个以硬脑膜为基底的左侧颞叶大肿瘤,伴有相邻的血管源性水肿。患者为进行术前肿瘤栓塞术接受了脑血管造影,结果显示一个小的、未破裂的颅内动脉瘤,起源于左侧ACA近端A1段。我们进行了左额颞开颅手术,同时切除以硬脑膜为基底的肿瘤并夹闭左侧A1段动脉瘤。她选择继续手术,因此接受了左侧开颅手术以切除肿瘤并夹闭动脉瘤。术后,患者因左侧丘脑前梗死出现短暂性轻度右侧偏瘫,出院前症状缓解。随访脑磁共振成像和导管脑血管造影分别显示肿瘤全切和动脉瘤完全闭塞。患有脑肿瘤和颅内动脉瘤双重诊断的患者管理起来可能具有挑战性。当对每个病变都需要进行干预且两者都可以通过相同的手术入路安全处理时,在适当选择的病例中同期手术治疗肿瘤和动脉瘤是合理的。