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在参与英国 Parkrun 的休闲跑者中使用口服非甾体抗炎药:使用率和风险意识。

Oral non-steroidal anti-inflammatory drug use in recreational runners participating in Parkrun UK: Prevalence of use and awareness of risk.

机构信息

Centre for Sports and Exercise Medicine, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.

School of Pharmacy, University of Birmingham, Birmingham, UK.

出版信息

Int J Pharm Pract. 2020 Dec;28(6):561-568. doi: 10.1111/ijpp.12646. Epub 2020 Jun 21.

Abstract

OBJECTIVE

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in endurance running and by elite athletes. We examined the pattern of use of NSAIDs, the purpose of use and knowledge of the adverse effects of NSAID use in a population of recreational runners at Parkrun UK.

METHODS

An online observational non-interventional cross-sectional survey of Parkrun UK participants being over the age of 18, on Parkrun UK's mailing list, and residing in the UK.

KEY FINDINGS

Runners (n = 806) had a high use of NSAIDs in the past 12 months (87.8%). The average age of respondents was 48.39 years. There was a significant association between those taking an oral NSAID in the last twelve months and those with a sporting injury (χ  = 10.89, df = 1, n = 797, P = 0.001). Ibuprofen was the most commonly used NSAID (81.1%). A third of runners had experienced an adverse drug reaction associated with NSAIDs, usually gastrointestinal. Half of runners used NSAIDs with no advice, and patient information leaflets were the most common source for those that had advice. Ninety-four per cent of runners would like more information on the harms and benefits of NSAIDs.

CONCLUSIONS

Some recreational runners have a high use of NSAIDs, which is chronic in nature and a potential health risk. Recreational runners want more information on the harms and benefits of NSAIDs. Race event organizers should provide evidence-based advice on the use of NSAIDs.

摘要

目的

非甾体抗炎药(NSAIDs)在耐力跑和精英运动员中广泛使用。我们在英国 Parkrun 中调查了 NSAIDs 的使用模式、使用目的以及对 NSAIDs 使用不良反应的了解程度,这是一个休闲跑者人群。

方法

一项针对年龄超过 18 岁、在英国 Parkrun 邮件列表上且居住在英国的英国 Parkrun 参与者的在线观察性非干预性横断面调查。

主要发现

过去 12 个月内,跑者(n=806)大量使用 NSAIDs(87.8%)。受访者的平均年龄为 48.39 岁。在过去 12 个月内服用口服 NSAIDs 的人与有运动损伤的人之间存在显著关联(χ²=10.89,df=1,n=797,P=0.001)。布洛芬是最常用的 NSAID(81.1%)。三分之一的跑者经历过与 NSAIDs 相关的不良反应,通常是胃肠道问题。一半的跑者在没有任何建议的情况下使用 NSAIDs,而患者用药指南是最常见的有建议的来源。94%的跑者希望获得更多关于 NSAIDs 的危害和益处的信息。

结论

一些休闲跑者大量使用 NSAIDs,这种情况是慢性的,存在潜在的健康风险。休闲跑者希望获得更多关于 NSAIDs 的危害和益处的信息。赛事组织者应提供有关 NSAIDs 使用的基于证据的建议。

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