• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

低蛋白血症是腹腔感染患者死亡的预测因子。

Hypoalbuminemia as a predictor of mortality in abdominal sepsis.

机构信息

Servicio de Cirugía General, Hospital Ángeles MOCEL, Ciudad de México, México.

出版信息

Cir Cir. 2020;88(4):481-484. doi: 10.24875/CIRU.20001712.

DOI:10.24875/CIRU.20001712
PMID:32567597
Abstract

BACKGROUND

A level < 35 g/L of albumin (hypoalbuminemia) has been determined as a parameter to predict mortality and morbidity.

METHOD

Prospective observational study, in a period of 12 months, to patients diagnosed with sepsis of abdominal origin, they are divided into two groups based on albumin levels (cut: 3.5 g/dL) to assess mortality between both groups.

RESULTS

We studied 23 patients admitted to the intensive care unit. The mean albumin was 2.77 g/dL (± 0.71). When calculating the odds ratio (OR) that was a 23-fold greater risk of dying when hypoalbuminemia presented compared to the normal albumin group (OR = 23.3; 95% CI: 1,948 to 279.42). The mean albumin for patients who died was 2.04 g/dL (± 0.31) vs. 3.03 g/dL (± 0.35) (p = 0.02; 95% CI: -1.551 to -0.416). We do not assess morbidity, however, we identify a certain tendency to a longer stay in the ICU which is accompanied by a higher risk of complications and in the end a higher risk of mortality.

CONCLUSION

We conclude that hypoalbuminemia represents a predictor of mortality in patients with abdominal sepsis.

摘要

背景

白蛋白水平 < 35 g/L(低白蛋白血症)已被确定为预测死亡率和发病率的参数。

方法

前瞻性观察研究,在 12 个月的时间内,对诊断为腹部来源脓毒症的患者进行研究,根据白蛋白水平(切点:3.5 g/dL)将患者分为两组,以评估两组之间的死亡率。

结果

我们研究了 23 名入住重症监护病房的患者。白蛋白的平均值为 2.77 g/dL(± 0.71)。当计算白蛋白水平较低时死亡的优势比(OR)时,与正常白蛋白组相比,死亡风险增加了 23 倍(OR = 23.3;95%CI:1.948 至 279.42)。死亡患者的白蛋白平均值为 2.04 g/dL(± 0.31),而 3.03 g/dL(± 0.35)(p = 0.02;95%CI:-1.551 至-0.416)。我们没有评估发病率,但是,我们发现 ICU 住院时间延长的趋势,这伴随着并发症风险增加,最终死亡率增加。

结论

我们得出结论,低白蛋白血症是腹部脓毒症患者死亡率的预测因素。

相似文献

1
Hypoalbuminemia as a predictor of mortality in abdominal sepsis.低蛋白血症是腹腔感染患者死亡的预测因子。
Cir Cir. 2020;88(4):481-484. doi: 10.24875/CIRU.20001712.
2
Sepsis patients with complication of hypoglycemia and hypoalbuminemia are an early and easy identification of high mortality risk.合并低血糖和低白蛋白血症的脓毒症患者是一种早期且容易识别的高死亡率风险。
Intern Emerg Med. 2019 Jun;14(4):539-548. doi: 10.1007/s11739-019-02034-2. Epub 2019 Feb 7.
3
Is albumin a predictor of severity and mortality in patients with abdominal sepsis?白蛋白是腹部脓毒症患者病情严重程度和死亡率的预测指标吗?
Cir Cir. 2019;87(5):485-489. doi: 10.24875/CIRU.180003903.
4
Hypoalbuminemia is a strong predictor of 30-day all-cause mortality in acutely admitted medical patients: a prospective, observational, cohort study.低白蛋白血症是急性收治内科患者30天全因死亡率的有力预测指标:一项前瞻性观察性队列研究。
PLoS One. 2014 Aug 22;9(8):e105983. doi: 10.1371/journal.pone.0105983. eCollection 2014.
5
The impact of admission hyperglycemia or hypoalbuminemia on need ventilator, time ventilated, mortality, and morbidity in critically ill trauma patients.入院时高血糖或低白蛋白血症对重症创伤患者使用呼吸机的需求、通气时间、死亡率和发病率的影响。
Ulus Travma Acil Cerrahi Derg. 2009 Mar;15(2):120-9.
6
Predictive Value of Serum Albumin Level for the Prognosis of Severe Sepsis Without Exogenous Human Albumin Administration: A Prospective Cohort Study.血清白蛋白水平对未使用外源性人白蛋白的严重脓毒症患者预后的预测价值:一项前瞻性队列研究。
J Intensive Care Med. 2018 Dec;33(12):687-694. doi: 10.1177/0885066616685300. Epub 2016 Dec 26.
7
Preoperative hypoalbuminemia is associated with poor clinical outcomes after open and endovascular abdominal aortic aneurysm repair.术前低白蛋白血症与开放和血管腔内腹主动脉瘤修复术后不良临床结局相关。
J Vasc Surg. 2017 Jul;66(1):53-63.e1. doi: 10.1016/j.jvs.2016.10.110. Epub 2017 Feb 16.
8
Predictive performance of quick Sepsis-related Organ Failure Assessment for mortality and ICU admission in patients with infection at the ED.急诊科感染患者中快速脓毒症相关器官功能衰竭评估对死亡率和入住重症监护病房的预测性能。
Am J Emerg Med. 2016 Sep;34(9):1788-93. doi: 10.1016/j.ajem.2016.06.015. Epub 2016 Jun 7.
9
[Analysis of death risk factors for nosocomial infection patients in an ICU: a retrospective review of 864 patients from 2009 to 2015].[重症监护病房医院感染患者死亡危险因素分析:对2009年至2015年864例患者的回顾性研究]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2016 Aug;28(8):704-8. doi: 10.3760/cma.j.issn.2095-4352.2016.08.007.
10
Correlation of lactate/albumin ratio level to organ failure and mortality in severe sepsis and septic shock.严重脓毒症和脓毒性休克中乳酸/白蛋白比值水平与器官衰竭及死亡率的相关性
J Crit Care. 2015 Apr;30(2):271-5. doi: 10.1016/j.jcrc.2014.10.030. Epub 2014 Nov 11.

引用本文的文献

1
Prediction of the mortality rate in the intensive care unit for early sepsis patients with combined hypoalbuminemia based on machine learning.基于机器学习对合并低白蛋白血症的早期脓毒症患者重症监护病房死亡率的预测
Medicine (Baltimore). 2025 Aug 1;104(31):e43610. doi: 10.1097/MD.0000000000043610.
2
Association between the lactate-albumin ratio and microcirculation changes in Pediatric Septic patients.乳酸-白蛋白比值与小儿脓毒症患者微循环变化的关系。
Sci Rep. 2024 Sep 29;14(1):22579. doi: 10.1038/s41598-024-73112-5.
3
Prediction of Poor Outcome Using the Urea to Albumin Ratio in Thoracic Empyema.
利用胸腔积液中尿素与白蛋白比值预测不良预后
Acta Med Litu. 2024;31(1):160-168. doi: 10.15388/Amed.2024.31.1.21. Epub 2024 Feb 27.
4
Serum Lactate-Albumin Ratio: Soothsayer for Outcome in Sepsis.血清乳酸-白蛋白比值:脓毒症预后的预测指标
Cureus. 2023 Mar 28;15(3):e36816. doi: 10.7759/cureus.36816. eCollection 2023 Mar.
5
Clinical value of procalcitonin-to-albumin ratio for identifying sepsis in neonates with pneumonia.降钙素原与白蛋白比值对新生儿肺炎合并脓毒症的临床价值。
Ann Med. 2023 Dec;55(1):920-925. doi: 10.1080/07853890.2023.2185673.
6
Development and Validation of a Predictive Scoring System for In-hospital Death in Patients With Intra-Abdominal Infection: A Single-Center 10-Year Retrospective Study.腹内感染患者院内死亡预测评分系统的开发与验证:一项单中心10年回顾性研究
Front Med (Lausanne). 2021 Nov 12;8:741914. doi: 10.3389/fmed.2021.741914. eCollection 2021.
7
Hypoalbuminemia as Surrogate and Culprit of Infections.低白蛋白血症:感染的替代指标和致病因素。
Int J Mol Sci. 2021 Apr 26;22(9):4496. doi: 10.3390/ijms22094496.