Godinez-Vidal Ansony R, Correa-Montoya Andrew, Enríquez-Santos Diana, Pérez-Escobedo Sergio U, López-Romero Sandra C, Gracida-Mancilla Noé I
Departamento de Cirugía General. Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México.
Departamento de Anestesiología. Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México.
Cir Cir. 2019;87(5):485-489. doi: 10.24875/CIRU.180003903.
Patients with a lower level of albumin have a more severe infection, the level of said biomarker is a strong predictor of mortality.
To determine the usefulness of the serum albumin level as a predictor of severity and mortality.
Retrospective, descriptive, cross-sectional study of patients diagnosed with abdominal sepsis. During the period from April 2016-February 2017. The severity was determined by Acute Physiology and Chronic Health Evaluation (APACHE) II, Sequential Organ Failure Assessment (SOFA), Mannheim and mortality. The sample was divided into those with albumin > 2.9 mg/dl and < 2.8 mg/dl.
We included 155 cases, 62 female and 93 male; the main organ causing abdominal sepsis was the appendix 42%. The average albumin for the sample was 3.2 mg/dl (DE ± 0.9). The findings, subjected to statistical verification by means of the Mann-Whitney test, showed statistical significance among the cases with albumin < 2.8 mg/dl with those have ranged Mannheim > 26 points (p = 0.001), APACHE > 15 (p = 0.015) and SOFA > 6 (p = 0.001), No statistical significance was obtained between albumin level < 2.8, and mortality (p = 0.052).
Albumin can be considered as a predictor of severity, although not as a predictor of mortality.
白蛋白水平较低的患者感染更严重，该生物标志物水平是死亡率的有力预测指标。
确定血清白蛋白水平作为严重程度和死亡率预测指标的有效性。
对诊断为腹部脓毒症的患者进行回顾性、描述性横断面研究。研究时间为2016年4月至2017年2月。通过急性生理与慢性健康状况评分系统（APACHE）II、序贯器官衰竭评估（SOFA）、曼海姆评分来确定严重程度及死亡率。样本分为白蛋白>2.9mg/dl和<2.8mg/dl两组。
我们纳入了155例病例，其中女性62例，男性93例；导致腹部脓毒症的主要器官是阑尾，占42%。样本的平均白蛋白水平为3.2mg/dl（标准差±0.9）。通过曼-惠特尼检验进行统计验证的结果显示，白蛋白<2.8mg/dl的病例与曼海姆评分>26分（p = 0.001）、APACHE>15（p = 0.015）和SOFA>6（p = 0.001）的病例之间存在统计学意义。白蛋白水平<2.8与死亡率之间未获得统计学意义（p = 0.052）。
白蛋白可被视为严重程度的预测指标，但不能作为死亡率的预测指标。
