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法国产高毒力肺炎克雷伯菌 K2-ST86 携带 blaOXA-48 型碳青霉烯酶导致的碳青霉烯耐药性。

Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae, France.

出版信息

Emerg Infect Dis. 2020 Jul;26(7):1529-1533. doi: 10.3201/eid2607.191490.

DOI:10.3201/eid2607.191490
PMID:32568057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7323517/
Abstract

We recovered 2 carbapenem-resistant K2-ST86 hypermucoviscous Klebsiella pneumoniae isolates from patients in France. The isolates had genetic attributes of hypervirulent K. pneumoniae but differed in ability to cause mouse lethality. Convergence of hypervirulent K. pneumoniae toward resistance could cause a health crisis because such strains could be responsible for severe and untreatable infections.

摘要

我们从法国的患者中分离到了 2 株耐碳青霉烯类的 K2-ST86 超黏菌素肺炎克雷伯菌。这些分离株具有高毒力肺炎克雷伯菌的遗传特征，但导致小鼠致死的能力不同。高毒力肺炎克雷伯菌向耐药性的趋同可能会引发健康危机，因为这些菌株可能导致严重且无法治疗的感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e0e/7323517/a234ebedb6d6/19-1490-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e0e/7323517/45717a045efd/19-1490-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e0e/7323517/a234ebedb6d6/19-1490-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e0e/7323517/45717a045efd/19-1490-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e0e/7323517/a234ebedb6d6/19-1490-F2.jpg

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