两株产碳青霉烯酶高毒力肺炎克雷伯菌分离株来自加拿大患者。
Two Hypervirulent Klebsiella pneumoniae Isolates Producing a Carbapenemase from a Canadian Patient.
机构信息
Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Jewish General Hospital, Montreal, Quebec, Canada
出版信息
Antimicrob Agents Chemother. 2019 Jun 24;63(7). doi: 10.1128/AAC.00517-19. Print 2019 Jul.
Abstract
This report describes two hypervirulent isolates that produced carbapenemase (KPC), which were identified from a rectal swab and a urine culture upon hospital admission. The patient had recently traveled to Greece, where he was hospitalized. The isolates were sequence type 86 and contained an IncHI1B IncFIB hypervirulent plasmid and an IncFII plasmid harboring KPC.
摘要
本报告描述了两株产碳青霉烯酶（KPC）的高毒力分离株，它们分别从入院时的直肠拭子和尿液培养中鉴定出来。该患者最近曾前往希腊住院。这些分离株的序列类型为 86，包含一个 IncHI1B IncFIB 高毒力质粒和一个携带 KPC 的 IncFII 质粒。
相似文献
1
Two Hypervirulent Klebsiella pneumoniae Isolates Producing a Carbapenemase from a Canadian Patient.两株产碳青霉烯酶高毒力肺炎克雷伯菌分离株来自加拿大患者。
Antimicrob Agents Chemother. 2019 Jun 24;63(7). doi: 10.1128/AAC.00517-19. Print 2019 Jul.
2
Identification of a Carbapenemase-Producing Hypervirulent Klebsiella pneumoniae Isolate in the United States.鉴定美国产高产毒碳青霉烯酶肺炎克雷伯菌。
Antimicrob Agents Chemother. 2019 Jun 24;63(7). doi: 10.1128/AAC.00519-19. Print 2019 Jul.
3
Molecular Epidemiology of Hypervirulent Carbapenemase-Producing .产超广谱碳青霉烯酶高毒力.的分子流行病学
Front Cell Infect Microbiol. 2021 Apr 7;11:661218. doi: 10.3389/fcimb.2021.661218. eCollection 2021.
4
Virulence genes in isolates of Klebsiella pneumoniae from the UK during 2016, including among carbapenemase gene-positive hypervirulent K1-ST23 and 'non-hypervirulent' types ST147, ST15 and ST383.2016年英国肺炎克雷伯菌分离株中的毒力基因，包括碳青霉烯酶基因阳性的高毒力K1-ST23型以及“非高毒力”型ST147、ST15和ST383。
J Med Microbiol. 2018 Jan;67(1):118-128. doi: 10.1099/jmm.0.000653. Epub 2017 Dec 5.
5
Emergence of OXA-232 Carbapenemase-Producing That Carries a pLVPK-Like Virulence Plasmid among Elderly Patients in China.产 OXA-232 碳青霉烯酶 携带 pLVPK 样毒力质粒的老年患者在中国出现。
Antimicrob Agents Chemother. 2019 Feb 26;63(3). doi: 10.1128/AAC.02246-18. Print 2019 Mar.
6
Emergence of KPC-producing Klebsiella pneumoniae hypervirulent clone of capsular serotype K1 that belongs to sequence type 11 in Mainland China.中国大陆出现产KPC的肺炎克雷伯菌高毒力克隆株，其为荚膜血清型K1且属于序列型11。
Diagn Microbiol Infect Dis. 2016 Jun;85(2):192-4. doi: 10.1016/j.diagmicrobio.2015.03.012. Epub 2015 Mar 21.
7
Emergence of bla KPC-3-Tn4401a associated with a pKPN3/4-like plasmid within ST384 and ST388 Klebsiella pneumoniae clones in Spain.西班牙产 ST384 和 ST388 肺炎克雷伯菌克隆中出现的 bla KPC-3-Tn4401a 与 pKPN3/4 样质粒相关。
J Antimicrob Chemother. 2010 Aug;65(8):1608-14. doi: 10.1093/jac/dkq174. Epub 2010 May 30.
8
Emergence of IMP-producing hypervirulent Klebsiella pneumoniae carrying a pLVPK-like virulence plasmid.携带pLVPK样毒力质粒的产IMP的高毒力肺炎克雷伯菌的出现。
Int J Antimicrob Agents. 2019 Jun;53(6):873-875. doi: 10.1016/j.ijantimicag.2019.05.007. Epub 2019 May 7.
9
Emergence of clonally related Klebsiella pneumoniae isolates of sequence type 258 producing plasmid-mediated KPC carbapenemase in Norway and Sweden.挪威和瑞典出现序列型258的克隆相关肺炎克雷伯菌分离株，这些分离株产生质粒介导的KPC碳青霉烯酶。
J Antimicrob Chemother. 2009 Apr;63(4):654-8. doi: 10.1093/jac/dkp018. Epub 2009 Feb 13.
10
Emergence of a Multidrug-Resistant Hypervirulent Klebsiella pneumoniae Sequence Type 23 Strain with a Rare -Harboring Virulence Plasmid.一株携带罕见毒力质粒的多重耐药高毒力肺炎克雷伯菌 23 型的出现。
Antimicrob Agents Chemother. 2019 Feb 26;63(3). doi: 10.1128/AAC.02273-18. Print 2019 Mar.
引用本文的文献
1
Global emergence of Carbapenem-resistant Hypervirulent Klebsiella pneumoniae driven by an IncFII KPC-2 plasmid.由IncFII KPC-2质粒驱动的耐碳青霉烯类高毒力肺炎克雷伯菌在全球出现。
EBioMedicine. 2025 Mar;113:105627. doi: 10.1016/j.ebiom.2025.105627. Epub 2025 Mar 1.
2
Virulence Factors and Carbapenem-Resistance Mechanisms in Hypervirulent .高毒力菌株中的毒力因子与碳青霉烯类耐药机制
Infect Drug Resist. 2024 Apr 20;17:1551-1559. doi: 10.2147/IDR.S461903. eCollection 2024.
3
Virulence factors in carbapenem-resistant hypervirulent .耐碳青霉烯类高毒力菌中的毒力因子
Front Microbiol. 2023 Nov 30;14:1325077. doi: 10.3389/fmicb.2023.1325077. eCollection 2023.
4
Expansion of healthcare-associated hypervirulent KPC-2-producing ST11/KL64 beyond hospital settings.产超毒力KPC-2的ST11/KL64型菌株在医疗保健相关环境之外的传播。
One Health. 2023 Jun 26;17:100594. doi: 10.1016/j.onehlt.2023.100594. eCollection 2023 Dec.
5
Bacteriological characteristics of hypervirulent gene (hvKp-)-harboring strains in the south of Iran.伊朗南部携带高毒力基因（hvKp-）菌株的细菌学特征
Iran J Microbiol. 2022 Aug;14(4):475-483. doi: 10.18502/ijm.v14i4.10233.
6
The Klebsiella pneumoniae Operon Enhances Stress Tolerance.肺炎克雷伯氏菌操纵子增强应激耐受性。
Infect Immun. 2023 Feb 16;91(2):e0055922. doi: 10.1128/iai.00559-22. Epub 2023 Jan 18.
7
The making of hypervirulent Klebsiella pneumoniae.产超毒力肺炎克雷伯菌的形成。
J Clin Lab Anal. 2022 Dec;36(12):e24743. doi: 10.1002/jcla.24743. Epub 2022 Nov 8.
8
Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent .耐碳青霉烯类高毒力菌的流行病学特征及分子进化机制
Front Microbiol. 2022 Sep 12;13:1003783. doi: 10.3389/fmicb.2022.1003783. eCollection 2022.
9
Global spread and evolutionary convergence of multidrug-resistant and hypervirulent high-risk clones.全球传播和多重耐药性及高毒力高危克隆的进化趋同。
Pathog Glob Health. 2023 Jun;117(4):328-341. doi: 10.1080/20477724.2022.2121362. Epub 2022 Sep 11.
10
Molecular and clinical characterization of hypervirulent isolates from individuals with urinary tract infections.从尿路感染患者中分离的高毒力株的分子和临床特征。
Front Cell Infect Microbiol. 2022 Aug 8;12:925440. doi: 10.3389/fcimb.2022.925440. eCollection 2022.
本文引用的文献
1
Emergence of OXA-232 Carbapenemase-Producing That Carries a pLVPK-Like Virulence Plasmid among Elderly Patients in China.产 OXA-232 碳青霉烯酶 携带 pLVPK 样毒力质粒的老年患者在中国出现。
Antimicrob Agents Chemother. 2019 Feb 26;63(3). doi: 10.1128/AAC.02246-18. Print 2019 Mar.
2
A case of NDM-carbapenemase-producing hypervirulent sequence type 23 from the UK.来自英国的一例产NDM-碳青霉烯酶的高毒力序列型23菌株。
JMM Case Rep. 2018 May 17;5(9):e005130. doi: 10.1099/jmmcr.0.005130. eCollection 2018 Sep.
3
Carriage of blaKPC-2 by a virulence plasmid in hypervirulent Klebsiella pneumoniae.产 blaKPC-2 超毒力肺炎克雷伯菌中携带毒力质粒。
J Antimicrob Chemother. 2018 Dec 1;73(12):3317-3321. doi: 10.1093/jac/dky358.
4
Emergence of tet(A) and bla co-carrying plasmid from a ST11 hypervirulent Klebsiella pneumoniae isolate in patient's gut.从患者肠道中一株ST11型高毒力肺炎克雷伯菌分离株中出现携带tet(A)和bla的质粒。
Int J Antimicrob Agents. 2018 Aug;52(2):307-308. doi: 10.1016/j.ijantimicag.2018.06.003. Epub 2018 Jun 10.
5
Antimicrobial Resistance of Hypervirulent : Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms.高毒力 耐药性：流行病学、高毒力相关决定因素和耐药机制。
Front Cell Infect Microbiol. 2017 Nov 21;7:483. doi: 10.3389/fcimb.2017.00483. eCollection 2017.
6
A fatal outbreak of ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study.中国医院中致命的 ST11 碳青霉烯类耐药超毒力肺炎克雷伯菌爆发：一项分子流行病学研究。
Lancet Infect Dis. 2018 Jan;18(1):37-46. doi: 10.1016/S1473-3099(17)30489-9. Epub 2017 Aug 29.
7
Results from the Canadian Nosocomial Infection Surveillance Program on Carbapenemase-Producing Enterobacteriaceae, 2010 to 2014.2010年至2014年加拿大医院感染监测项目关于产碳青霉烯酶肠杆菌科细菌的结果。
Antimicrob Agents Chemother. 2016 Oct 21;60(11):6787-6794. doi: 10.1128/AAC.01359-16. Print 2016 Nov.
8
ESBL-Producing Strain of Hypervirulent Klebsiella pneumoniae K2, France.产超广谱β-内酰胺酶的高毒力肺炎克雷伯菌K2菌株，法国
Emerg Infect Dis. 2016 Sep;22(9):1687-8. doi: 10.3201/eid2209.160681.
9
High Prevalence of Hypervirulent Klebsiella pneumoniae Infection in China: Geographic Distribution, Clinical Characteristics, and Antimicrobial Resistance.中国高毒力肺炎克雷伯菌感染的高流行率：地理分布、临床特征及抗菌药物耐药性
Antimicrob Agents Chemother. 2016 Sep 23;60(10):6115-20. doi: 10.1128/AAC.01127-16. Print 2016 Oct.
10
Multilocus Sequence Types and Virulence Determinants of Hypermucoviscosity-Positive Klebsiella pneumoniae Isolated from Community-Acquired Infection Cases in Harbin, North China.从中国北方哈尔滨社区获得性感染病例中分离出的高黏液性肺炎克雷伯菌的多位点序列类型及毒力决定因素
Jpn J Infect Dis. 2016 Sep 21;69(5):357-60. doi: 10.7883/yoken.JJID.2015.321. Epub 2016 Jan 8.
Zotero 插件