Institutional affiliation: Phoenix Children's Hospital; Departments of Surgery and Child Health, Univeristy of Arizona, Phoenix, AZ; Department of Surgery, Creighton University School of Medicine, Phoenix, AZ; Departments of Surgery and Pediatrics, Mayo Clinic Arizona, Phoenix, AZ.
Semin Pediatr Surg. 2020 Jun;29(3):150923. doi: 10.1016/j.sempedsurg.2020.150923. Epub 2020 May 17.
Parathyroid glands are critical for calcium and phosphate homeostasis. Parathyroid disease is relatively rare in the pediatric population, but there are some important pediatric-specific considerations and conditions. This article reviews parathyroid physiology, disorders of hyper- and hypo- function, operative management, and uniquely pediatric diagnoses such as neonatal severe hyperparathyroidism. Advances in preoperative imaging, intra-operative gland identification, and management of post-thyroidectomy hypocalcemia are also presented in detail. This article combines a review of fundamentals with recent advances in care, emphasizing pediatric-specific publications.
甲状旁腺对于钙和磷的体内平衡至关重要。甲状旁腺疾病在儿科人群中相对罕见,但存在一些重要的儿科特有考虑因素和情况。本文回顾了甲状旁腺的生理学、功能亢进和功能减退障碍、手术治疗以及新生儿严重甲状旁腺功能亢进等独特的儿科诊断。本文还详细介绍了术前影像学、术中腺体识别以及甲状腺切除术后低钙血症管理方面的最新进展。本文结合了基础知识的回顾和最新的治疗进展,强调了儿科特有的出版物。