MediWiSe| Medical Wireless Sensing Ltd, Queen Mary Bio Enterprise Innovation Centre, 42 New Road, E1 2AX, London, UK.
Metamaterial Inc, 1 Research Drive, Dartmouth, Nova Scotia, B2Y 4M9, Canada.
Sci Rep. 2020 Jun 22;10(1):10042. doi: 10.1038/s41598-020-66884-z.
We present a radio-frequency-activated switching system that can automatically detune a metamaterial resonator to enhance magnetic resonance imaging (MRI) performance. Local sensitivity-enhancing metamaterials typically consist of resonant components, which means that the transmitted radio frequency field is spatially inhomogeneous. The switching system shows for the first time that a metamaterial resonator can be detuned during transmission and tuned during reception using a digital circuit. This allows a resonating system to maintain homogeneous transmit field while maintaining an increased receive sensitivity. As a result, sensitivity can be enhanced without changing the system-provided specific absorption rate (SAR) models. The developed digital circuit consists of inductors sensitive to the transmit radio-frequency pulses, along with diodes acting as switches to control the resonance frequency of the resonator. We first test the automatic resonator detuning on-the-bench, and subsequently evaluate it in a 1.5 T MRI scanner using tissue-mimicking phantoms. The scan results demonstrate that the switching mechanism automatically detunes the resonator in transmit mode, while retaining its sensitivity-enhancing properties (tuned to the Larmor frequency) in receive mode. Since it does not require any connection to the MRI console, the switching system can have broad applications and could be adapted for use with other types of MRI scanners and field-enhancing resonators.
我们提出了一种射频激活切换系统,该系统可以自动调谐超材料谐振器,以提高磁共振成像(MRI)性能。局部灵敏度增强超材料通常由谐振元件组成,这意味着传输的射频场是空间不均匀的。该切换系统首次表明,超材料谐振器可以在传输过程中进行调谐,在接收过程中使用数字电路进行调谐。这允许谐振系统在保持均匀的发射场的同时,保持更高的接收灵敏度。因此,可以在不改变系统提供的特定吸收率(SAR)模型的情况下提高灵敏度。所开发的数字电路由对发射射频脉冲敏感的电感器组成,以及用作开关的二极管,以控制谐振器的谐振频率。我们首先在台式机上测试了自动调谐器的调谐,然后在 1.5T MRI 扫描仪上使用组织模拟体模对其进行了评估。扫描结果表明,切换机制可在发射模式下自动调谐谐振器,同时在接收模式下保持其增强灵敏度的特性(调谐到拉莫尔频率)。由于它不需要与 MRI 控制台连接,因此该切换系统具有广泛的应用前景,可以适应其他类型的 MRI 扫描仪和场增强谐振器。